Acute effects of repeated bouts of aerobic exercise on arterial stiffness after glucose ingestion

Abstract

RE trial repeated bouts of aerobic exercise trial; CON trial control trial; BG blood glucose; VO peak oxygen uptake; PWV Pulse wave velocity; AIx carotid augmentation index; BP blood pressure; HR heart rate; CVs coefficients of variation; RPE Ratings of perceived exertion; SE standard error.

No impact of acute hyperglycaemia on arterial stiffness in the early and late follicular phases of the menstrual cycle in young females

“…In contrast to the present findings in young women, some previous research in men and postmenopausal women has reported increases in arterial stiffness with hyperglycaemia (Baynard et al., ; Gordin et al., ; Huang et al., ; Kobayashi et al., , , ; Mullan et al., ). Most directly comparable to the methods of the present study, Kobayashi and colleagues (, , ) found that leg but not aortic (carotid–femoral) PWV increased after acute hyperglycaemia in healthy young men. The augmentation index and other indices of wave reflection also appear to increase with acute hyperglycaemia in this population (Grassi et al., ; Huang et al., ; Mullan et al., ).…”

“…Contrary to our hypothesis, an oral glucose challenge did not change central or peripheral PWV, despite significant increases in blood glucose and insulin concnetrations. These findings suggest that premenopausal women may experience protection against the acute hyperglycaemiainduced increases in arterial stiffness previously reported in healthy populations (Gordin et al, 2007;Kobayashi et al, 2015Kobayashi et al, , 2018Kobayashi et al, , 2019Mullan et al, 2004).…”

“…In contrast to the present findings in young women, some previous research in men and postmenopausal women has reported increases in arterial stiffness with hyperglycaemia (Baynard et al, 2009;Gordin et al, 2007;Huang et al, 2007;Kobayashi et al, 2015Kobayashi et al, , 2018Kobayashi et al, , 2019Mullan et al, 2004). Most directly comparable to the methods of the present study, Kobayashi and colleagues (2015Kobayashi and colleagues ( , 2018Kobayashi and colleagues ( , 2019 found that leg but not aortic (carotid-femoral) PWV increased after acute hyperglycaemia in healthy young men.…”

“…Recent research demonstrates an inconsistent impact of acute hyperglycaemia on arterial stiffness that may vary with the vascular region examined and with the age and activity level of the study participants (Baynard, Carhart, Weinstock, Ploutz‐Snyder, & Kanaley, ; Credeur et al., ; Kobayashi, Hashimoto, Hatakeyama, & Okamoto, , ; Kobayashi, Yoshida, & Okamoto, ). Indices of systemic arterial stiffness (Grassi et al., ; Mullan, Ennis, Fee, Young, & McCance, ) and leg arterial stiffness assessed via pulse wave velocity (PWV) appear to increase in healthy untrained young men during acute hyperglycaemia (Kobayashi et al., , , ). However, aortic (central) stiffness, as reflected by the reference standard index carotid–femoral PWV, may not be altered by acute hyperglycaemia in healthy young men (Gordin et al., ; Kobayashi et al., , ).…”

“…Indices of systemic arterial stiffness (Grassi et al., ; Mullan, Ennis, Fee, Young, & McCance, ) and leg arterial stiffness assessed via pulse wave velocity (PWV) appear to increase in healthy untrained young men during acute hyperglycaemia (Kobayashi et al., , , ). However, aortic (central) stiffness, as reflected by the reference standard index carotid–femoral PWV, may not be altered by acute hyperglycaemia in healthy young men (Gordin et al., ; Kobayashi et al., , ). A major limitation of this body of literature is the absence of young, premenopausal women within the study populations.…”