Acute Effects of Some Volatile Organic Compounds Emitted From Water-Based Paints

Abstract

Exposure to G and GA caused mild irritation in eyes, nose, and airways.

Ocular symptoms, tear film stability, nasal patency, and biomarkers in nasal lavage in indoor painters in relation to emissions from water-based paint

“…An association was also found between levels of 2-phenoxyethanol (range <0.001-0.30 mg/m 3 ) and impaired tear Wlm stability. An increase in ocular symptoms in relation to a 4-h exposure to a mixture of compounds commonly emitted from water-based paints was observed in an experimental exposure chamber study (Ernstgård et al 2007). The mixture contained propylene glycol (10 mg/m 3 ), Texanol (2,2,4-trimethyl 1,3-pentanediol monoisobutyrate (5 mg/m 3 ), diethylene glycol monoethyl ether (10 mg/m 3 ), diethylene glycol monobutyl ether (5 mg/m 3 ), and dipropylene glycol monomethyl ether (5 mg/m 3 ).…”

“…The mixture contained propylene glycol (10 mg/m 3 ), Texanol (2,2,4-trimethyl 1,3-pentanediol monoisobutyrate (5 mg/m 3 ), diethylene glycol monoethyl ether (10 mg/m 3 ), diethylene glycol monobutyl ether (5 mg/m 3 ), and dipropylene glycol monomethyl ether (5 mg/m 3 ). The eye irritation was observed both with and without additional exposure to ammonia (15 mg/m 3 ) (Ernstgård et al 2007). Moreover, an increase in eye symptoms has been reported in relation to indoor exposure to emissions from fresh paint (Norbäck et al 1994(Norbäck et al , 1996.…”

“…New-onset of asthma in a 2-year follow-up study in house painters was related to the estimated total exposure to VOC, mainly from SBP (Wieslander et al 1997). Potential hazard chemicals like biocides and various glycol ethers and ammonia have been studied, with mild irritative eVects in eyes, nose, and airways (Dahlqvist and Ulfvarsson 1997;Ernstgård et al 2007).…”

A field study on clinical signs and symptoms in cleaners at floor polish removal and application in a Swedish hospital

“…Only levels of DEGBE were higher during painting (mean 820 g/m 3 ) as compared to 67-71 g/m 3 at polishing work. In an experimental exposure chamber study on acute eVects during controlled exposure to a mixture of common volatile organic compounds in WBPs (propyleneglycol, texanol, DEGEE, DEGBE) at a total concentration of 35 mg/m 3 subjective ratings of irritation in eyes, nose, throat and dyspnoea were signiWcantly higher than compared to clean air in a chamber study (Ernstgard et al 2007). In this study no eVects were noticed on pulmonary function, or markers of inXammation in nasal lavage.…”

Upper Airway Mucosal Inflammation : Proteomic Studies after Exposure to Irritants and Microbial Agents

“…Also, microorganisms generate emissions of volatile organic compounds which are then referred to as microbial volatile organic compounds. One of the most common compounds is 3-methyl-1-butanol (3MB), although no clear effect has been found on humans [92]. Another microbial volatile organic compound is 1-octen-3-ol that has been associated with home-related mucous symptoms [93].…”