Acute interstitial pneumonia triggered by strenuous exercise

Markoska, Frosina; Lestan, David; Turel, Matjaž; Harlander, Matevž

doi:10.1016/j.rmcr.2020.101077

Cited by 2 publications

(1 citation statement)

References 16 publications

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“…Acute interstitial pneumonia (AIP) is a severe form of idiopathic acute interstitial disease affecting patients between 50 and 60 years of age associated to a poor prognosis with a mortality rate greater than 50%. Although the etiology is unknown, a case report was published that stated how acute interstitial pneumonia can be triggered by strenuous exercise [44]. In general, the clinical, radiological, and histological patterns are similar to those of acute respiratory distress syndrome (ARDS).…”

Section: Diagnosis and Histopathological Pattern Of Iipsmentioning

confidence: 99%

Fibrotic Idiopathic Interstitial Lung Disease: The Molecular and Cellular Key Players

Samarelli

Tonelli

Marchioni

et al. 2021

IJMS

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Interstitial lung diseases (ILDs) that are known as diffuse parenchymal lung diseases (DPLDs) lead to the damage of alveolar epithelium and lung parenchyma, culminating in inflammation and widespread fibrosis. ILDs that account for more than 200 different pathologies can be divided into two groups: ILDs that have a known cause and those where the cause is unknown, classified as idiopathic interstitial pneumonia (IIP). IIPs include idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonia (NSIP), cryptogenic organizing pneumonia (COP) known also as bronchiolitis obliterans organizing pneumonia (BOOP), acute interstitial pneumonia (AIP), desquamative interstitial pneumonia (DIP), respiratory bronchiolitis-associated interstitial lung disease (RB-ILD), and lymphocytic interstitial pneumonia (LIP). In this review, our aim is to describe the pathogenic mechanisms that lead to the onset and progression of the different IIPs, starting from IPF as the most studied, in order to find both the common and standalone molecular and cellular key players among them. Finally, a deeper molecular and cellular characterization of different interstitial lung diseases without a known cause would contribute to giving a more accurate diagnosis to the patients, which would translate to a more effective treatment decision.

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Section: Diagnosis and Histopathological Pattern Of Iipsmentioning

confidence: 99%