1996
DOI: 10.1016/s0920-9964(96)00037-0
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Acute phase proteins in male Chinese schizophrenic patients in Singapore

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Cited by 56 publications
(46 citation statements)
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“…Moreover, the negative subgroup showed a significant reduction in the bilirubin level. A significant reduction in the bilirubin and albumin levels was in line with previous findings, which suggested a similar direction in the antioxidant level [1,[3][4][5]7], supporting the hypothesis of an alteration in the antioxidant levels in schizophrenia patients. It is notable that the negative subgroup had a significantly lower bilirubin level, as suggested in a previous study, which showed that an altered antioxidant capacity may be associated with the symptomatology and treatment implications in schizophrenia, particularly negative symptoms [2].…”
Section: Discussionsupporting
confidence: 90%
See 1 more Smart Citation
“…Moreover, the negative subgroup showed a significant reduction in the bilirubin level. A significant reduction in the bilirubin and albumin levels was in line with previous findings, which suggested a similar direction in the antioxidant level [1,[3][4][5]7], supporting the hypothesis of an alteration in the antioxidant levels in schizophrenia patients. It is notable that the negative subgroup had a significantly lower bilirubin level, as suggested in a previous study, which showed that an altered antioxidant capacity may be associated with the symptomatology and treatment implications in schizophrenia, particularly negative symptoms [2].…”
Section: Discussionsupporting
confidence: 90%
“…Most recently, Reddy et al [5] have found that patients with firstepisode schizophrenia (FSPR) had significantly lower albumin, uric acid and bilirubin levels than normal controls, suggesting an early involvement of the defective antioxidant system in the course of illness regardless of antipsychotic effects. Neuropsychobiology 2004;50:54-56 55 However, there are few data showing a relationship between antioxidant levels in drug-naïve FSPR and risperidone-treated chronic schizophrenia (RCSPR) patients, in particular lacking in the Asian population [7]. Furthermore, there might be a difference in the antioxidant system according to the ethnic background [8].…”
Section: Introductionmentioning
confidence: 99%
“…It is important to mention that this metaanalysis controlled for potential confounding factors including age, gender and duration of illness. Other inflammation related proteins found to be increased in patients include complement system proteins such as complement C3 and C4 (Maes et al, 1997a;Wong et al, 1996).…”
Section: Immune Response and Inflammationmentioning
confidence: 99%
“…There are reports of C3 concentration decreases in chronic 70 and increases in drug-free patents. 71 However, the majority of the studies concluded nonsignificant or no alterations (Table II).…”
Section: Complement In Schizophreniamentioning
confidence: 99%