2022
DOI: 10.3389/fopht.2022.916113
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Acute retinal necrosis: A mini review

Abstract: Acute retinal necrosis is a rare but potentially devastating disease. Even in the era of modern medicine, retinal detachment is a frequent complication leading to vison loss, as well as phthisis bulbi. Whereas IV acyclovir still remains the standard of care, high doses of valacyclovir with/without additional intravitreal injections of foscarnet have been used. In an attempt to reduce the retinal detachment rate, prophylactic laser treatment and early vitrectomy have been proposed. In this article, we aim to re… Show more

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Cited by 4 publications
(1 citation statement)
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“…With respect to the posterior segment, HZO may result in ARN, which manifests as patches of peripheral retinitis that merge rapidly, accompanied by occlusive vasculitis and vitreous inflammation [ 29 , 48 ]. The acute phase of ARN may persist for 6–12 weeks [ 29 ] and often leads to retinal detachment within 3 weeks to 5 months of onset (Lau et al [ 57 ] cited in Hoogewoud et al [ 58 ]). As noted above, immunocompromised individuals are at particular risk of PORN [ 29 ].…”
Section: Clinical Presentationmentioning
confidence: 99%
“…With respect to the posterior segment, HZO may result in ARN, which manifests as patches of peripheral retinitis that merge rapidly, accompanied by occlusive vasculitis and vitreous inflammation [ 29 , 48 ]. The acute phase of ARN may persist for 6–12 weeks [ 29 ] and often leads to retinal detachment within 3 weeks to 5 months of onset (Lau et al [ 57 ] cited in Hoogewoud et al [ 58 ]). As noted above, immunocompromised individuals are at particular risk of PORN [ 29 ].…”
Section: Clinical Presentationmentioning
confidence: 99%