Acute retinal necrosis in a monocular patient complicated by acyclovir-induced nephrotoxicity

Minces, Lucio R.; Gallagher, Denise; Shields, Ryan K.

doi:10.1016/j.jcv.2010.04.016

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“…10 Moreover, plasma concentrations of valacyclovir are higher than those obtained with oral acyclovir. 1 In our case, we initiated valacyclovir after cessation of acyclovir and followed the patient closely with complete blood count and renal and liver function tests.…”

Section: Discussionmentioning

confidence: 99%

“…8 There have been only a few case reports of acyclovirinduced nephrotoxicity during ARN treatment in the published literature. 9,10 This nephrotoxicity is reversible in most cases with early diagnosis and discontinuation of the drug. 8 In our case, acyclovir nephrotoxicity developed despite adequate hydration and kidney improved after drug cessation.…”

Section: Discussionmentioning

confidence: 99%

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