Acute Spontaneous Mediastinal Emphysema

Hypertension

“…Where Clonidine is particularly useful is in patients who are already experiencing serious side‐effects with other hypotensive agents and where a change may improve the quality of the patient's life. In the recent comparative trial of Clonidine and guanethedine (Matts, 1973) patients were admitted to the trial in a randomized way and sequential analysis of the effects on blood pressure and of side‐effects were carried out using the technique of Snell and Armitage (1957) and Matts (1966). This showed by sequential analysis that Clonidine was preferred by a statistically significant number of patients because of the low incidence of side‐effects.…”

Advances in Treatment No. 7

“…In spite of this, antacid therapy does bring about symptomatic relief and its use is justified for this reason (Avery Jones, 1964;Kay, 1964), Ulcer healing, however, has been shown to be unaffected, even if the gastric pH is held above 4 throughout the 24 hours (Doll, Friedlander and Pygott, 1956;Doll, Price, Pygott and Sanderson, 1956), Symptomatic relief can be obtained with many antacid and antipeptic agents, I would select magnesium trisilicate, aluminium hydroxide and bismuth aluminate ('Bislumina') as being of particular value (Matts and Swan, 1964). Combinations of antacids with drugs to lower intestinal motility are also of some value, and I have recently found 'Kolanticon' Gel and Wafers to be of value in this situation (Matts, Swan and Kelleher, 1965;Matts, 1972).…”

“…I would select magnesium trisilicate, aluminium hydroxide and bismuth aluminate (‘Bislumina’) as being of particular value (Matts and Swan, 1964). Combinations of antacids with drugs to lower intestinal motility are also of some value, and I have recently found ‘Kolanticon’ Gel and Wafers to be of value in this situation (Matts, Swan and Kelleher, 1965; Matts, 1972).…”

Fatal Hyperpyrexia with Antidepressant Drugs

“…Nurses and teachers are in the majority in their professions, whereas men greatly outnumber women in the medical profession. As a corollary to equal pay, children's allowances should be paid to male personnel employed by the Government Survival of General Practice SIR,-I believe (1) The National Health Service, being a significant and worth-while experiment in the social progress of our generation, requires for its maintenance and development in the field of general practice the willing support of a contented profession, in partnership with a wise and progressive Ministry of Health.…”