Acute Toxicity, Analgesic Potential and Preliminary Antimocrobial Studies of the Aqueous Plant Extract of &lt;i&gt;Spilanthes Filicaulis&lt;/i&gt;

Ekor, Martins; Ashorobi, RB; Ibitoye, SF; Kasimi, LS

doi:10.4314/njhbs.v4i1.11534

Cited by 5 publications

(4 citation statements)

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“…Ethanol, as used in this study, proved to produce a Spilanthes extract, which proved to have a safe composition in the animal-model tests. The absence of subchronic toxicology was observed in other studies, as related by Zuluaga et al (2008) who administered an ethanolic extract of Spilanthes americana in Swiss albino mice, and by Ekor et al (2005) who evaluated an aqueous extract of Spilanthes filicaulis.…”

Section: Acute Toxicology Assaymentioning

confidence: 60%

Determination of toxicity and chromatographic analysis of spilanthol content in in vitro culture of Spilanthes oleracea Jacq.

Gesteira¹,

Simas²,

Morgana³

et al. 2018

Afr. J. Biotechnol.

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Spilanthes oleracea Jacq. has been extensively used due to its pharmacological activities, and it has been considered as a promising vegetable crop. Nodal-segment cultures of S. oleracea were established in order to analyze the content of alkamide spilanthol. On average, 11 buds/nodal segment were developed after 30 days on MS basal salts liquid medium containing 2.22 μM benzyladenine (BA). Regenerated shoots formed complete plantlets in medium without growth regulators, and 80.2% of the regenerated plantlets survived in field conditions. Higher production of spilanthol (58.5% relative area) was obtained from the leaves and stems of plants grown in liquid medium up to 90 days, than in fieldgrown plants. Addition of BA to the culture medium significantly affected spilanthol accumulation. The production of spilanthol was also detected on the shoot basal callus. The spilanthol content varied with the plant organ in micropropagated plants. Ethanolic extract of leaves from field-grown plants showed no acute toxicology in Swiss mice at a dosage of 3 g/kg.

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Section: Acute Toxicology Assaymentioning

confidence: 60%

Determination of toxicity and chromatographic analysis of spilanthol content in in vitro culture of Spilanthes oleracea Jacq.

Gesteira¹,

Simas²,

Morgana³

et al. 2018

Afr. J. Biotechnol.

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“…The antibacterial activities obtained validate the traditional uses of these plants in the treatment of infectious diseases. Ekor et al [22] earlier demonstrated the antibacterial activity of aqueous extract of S. filicaulis on urinary tract pathogens. Our study has made significant contribution because apart from the report of Ekor et al [22], this is one of the few reports revealing the antibacterial activity of various extracts, fractions and compounds from S. filicaulis on uropathogens.…”

Section: Discussionmentioning

confidence: 99%

“…Ekor et al [22] earlier demonstrated the antibacterial activity of aqueous extract of S. filicaulis on urinary tract pathogens. Our study has made significant contribution because apart from the report of Ekor et al [22], this is one of the few reports revealing the antibacterial activity of various extracts, fractions and compounds from S. filicaulis on uropathogens. Apparently, this is the first report on antibacterial activity of extracts, fractions and compounds from L. ovalifolia on the pathogens used in this study.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, the 40% hexane: 60% ethyl acetate fraction (I S ) of S. filicaulis also showed high activity, suggesting that some of the active components had intermediary polarity. In addition to this antibacterial activity, S. filicaulis has been reported to also possess analgesic properties [22], the probable reason for its use in treatment of toothache and stomachache in herbal medicine, and anti-inflammatory characteristics [9]. A related species to S. filicaulis, S. acmella Linn has been reported to possess remarkable inhibitory activity against human and agricultural fungal pathogens [26].…”

Section: Discussionmentioning

confidence: 99%

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In vitro Antimicrobial Activity of Agents from Spilanthes filicaulis and Laportea ovalifolia against Some Drug Resistant Bacteria

Akoachere

Yvonne

Mbah

et al. 2015

BJPR

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Spilanthes filicaulis (Schumach. &Thonn.) C. D. Adams: An insights into ethnopharmacologically important but scientifically understudied species

Ojo,

Olusola,

Ojo

2024

Annales Pharmaceutiques Françaises

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Acute Toxicity, Analgesic Potential and Preliminary Antimocrobial Studies of the Aqueous Plant Extract of <i>Spilanthes Filicaulis</i>

Cited by 5 publications

References 0 publications

Determination of toxicity and chromatographic analysis of spilanthol content in in vitro culture of Spilanthes oleracea Jacq.

Determination of toxicity and chromatographic analysis of spilanthol content in in vitro culture of Spilanthes oleracea Jacq.

In vitro Antimicrobial Activity of Agents from Spilanthes filicaulis and Laportea ovalifolia against Some Drug Resistant Bacteria

Spilanthes filicaulis (Schumach. &Thonn.) C. D. Adams: An insights into ethnopharmacologically important but scientifically understudied species

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