Adams Disease: Description and Management with Capsaicin and Heat

Abstract

Background/purpose: This work describes a new skin disease for the first time, Adams disease, and the management of the disease. Methods: Adams disease is caused by chafing and irritations, causes the skin to form rashes or thickening, crack and bleed. The skin is also sensitive to temperature and moisture changes and responds with itching and pain. Other symptoms include a swollen lower leg and a retina tear. Results: Adams disease of the fingers responds to hot water treatments. Capsaicin cream is effective against rashes anywhere on the body and thickening of the palms and soles of the feet. The swollen lower leg responds temporarily to hot water and oral steroids. Conclusion: Adams disease may be an auto-inflammatory disease caused by dysfunctional transient receptor potential cation vanilloid 1 channels. The disease is chronic, has exacerbations and remissions and can be managed with hot water treatments and capsaicin cream.

Varicose Veins, Retinal Tears and Deep Vein Thrombosis, New Insights into the Causes from Adams Disease

“…Adams disease is a disease caused by excessively active TRP [2]. The disease is characterized by pain in the skin, cracking and bleeding of the skin and other conditions.…”

Editorial: Apoptosis is Critical to Pain Control

“…This can activate apoptosis mechanisms that result in nerve terminal destruction [4]. This nerve terminal destruction in the skin is a prominent feature of Adams disease, a disease that involves severe pain from over activation of TRP channels by cold and other stimuli [5]. Adams disease appears to be caused by dysfunctional TRP receptors in the skin.…”