Introduction. Promotion of educational and scientific organization staff's subjective well-being in the conditions of war is an important research and applied problem, which requires, in particular, the study of its personality-related factors. Aim: to investigate the level of subjective well-being of the staff of educational and scientific organizations in the conditions of war and the relationship between well-being and coping strategies. Methods: The Modified BBC Subjective Well-being Scale (BBC-SWB) (P. Pontin, M. Schwannauer, S. Tai, & M. Kinderman; adapted by L. Karamushka, K. Tereshchenko, & O. Kredentser); The Coping Inventory for Stressful Situations (CISS) (N.S, Endler, J.D. Parker); statistical methods (descriptive statistics, correlation analysis (Pearson's correlation coefficient)). Results. In the conditions of war, staff of educational and scientific organizations was found to have subjective well-being at a moderate level. At the same time, the "physical health and well-being" indicator was almost half the level of the "psychological well-being" and "well-being in relationships" indicators. All subjective well-being indicators of educational and scientific organization staff's subjective well-being in the conditions of war had statistically significant, both positive and negative, relationship with the majority of coping strategies ("orientation towards problem solving", "social distraction", "orientation towards emotions", and "avoidance"), which suggests that coping strategies are a significant psychological factor in staff's subjective well-being. Conclusions. The obtained results can be helpful in improving performance of educational and scientific organizations in war conditions.