“…Furthermore, it is also important to consider the molecular size of the active molecules and their affinity with the substrate. Small hydrosoluble molecules or micrometric particles, such as calcium carbonate, kaolin, talc, alumina, and titanium oxide [ 65 , 66 , 67 ], often used as pigments, can penetrate deeper than macromolecules such as polyphenols (tannic acid, catechin) [ 68 , 69 ], polysaccharides (starch, chitin) [ 70 , 71 ], or other polymers (natural rubbers, polyesters, polysiloxane) [ 58 ] used for surface modification [ 67 ].…”