Addressing Discrepancies between Experimental and Computational Procedures

Toma, Milan; Guru, Satvinder K.; Wu, Wayne; Ali, May Mohammed; Ong, Chi Wei

doi:10.3390/biology10060536

Cited by 6 publications

(5 citation statements)

References 14 publications

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“…It is important to note that accuracy does not necessarily equate with realism if attained by altering the geometry employed in modeling. Therefore, it is imperative to strike a balance between computational efficiency and maintaining fidelity to real-world anatomical structures for meaningful medical research applications [48]. Likewise, the use of an FSI technique is essential to accurately study CSF behavior in scenarios where the brain experiences multiple acceleration and deceleration events.…”

Section: Discussionmentioning

confidence: 99%

Cushioning Effect of Conventional Padded Helmets on Interaction between Cerebrospinal Fluid and Brain after a Low-Speed Head Impact

et al. 2023

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Results of a recent experimental study challenge the widely-held belief that modern combat helmets are more effective at protecting soldiers against concussions. The research shows that helmets used during First World War without inner paddings may have an advantage in protecting soldiers’ brains from concussions when relying solely on cerebrospinal fluid. The present study explains this counterintuitive finding by revealing that while cerebrospinal fluid can prevent direct brain-to-skull contact during a single event, its protective capabilities diminish with each subsequent event occurring in quick succession—something conventional padded helmets appear to aggravate. The cerebrospinal fluid requires a certain amount of time to reset after an acceleration/deceleration event, which allows it to effectively provide cushioning for any subsequent events and protect against potential brain damage. However, an immediate occurrence of a subsequent event, when the fluid has no time to settle down, may significantly diminish the effectiveness of the fluid’s ability to provide adequate cushioning, thereby putting individuals at risk of serious injury. This new information may have implications for helmet design in the future and calls into question current assumptions regarding the best way to protect soldiers and athletes from concussions.

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Section: Discussionmentioning

confidence: 99%

Cushioning Effect of Conventional Padded Helmets on Interaction between Cerebrospinal Fluid and Brain after a Low-Speed Head Impact

et al. 2023

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“…It is crucial to account for these uncertainties as they can lead to erroneous computational analyses and geometric errors in the resulting model. In order to mitigate some sources of geometric error, preparation methods have been developed [103]. However, even with these methods, the resulting 3D geometry often does not accurately retain the original dimensions before excision from the body.…”

Section: Discussionmentioning

confidence: 99%

Modeling Dynamics of the Cardiovascular System Using Fluid-Structure Interaction Methods

Syed

Khan

Toma

2023

Biology

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Using fluid-structure interaction algorithms to simulate the human circulatory system is an innovative approach that can provide valuable insights into cardiovascular dynamics. Fluid-structure interaction algorithms enable us to couple simulations of blood flow and mechanical responses of the blood vessels while taking into account interactions between fluid dynamics and structural behaviors of vessel walls, heart walls, or valves. In the context of the human circulatory system, these algorithms offer a more comprehensive representation by considering the complex interplay between blood flow and the elasticity of blood vessels. Algorithms that simulate fluid flow dynamics and the resulting forces exerted on vessel walls can capture phenomena such as wall deformation, arterial compliance, and the propagation of pressure waves throughout the cardiovascular system. These models enhance the understanding of vasculature properties in human anatomy. The utilization of fluid-structure interaction methods in combination with medical imaging can generate patient-specific models for individual patients to facilitate the process of devising treatment plans. This review evaluates current applications and implications of fluid-structure interaction algorithms with respect to the vasculature, while considering their potential role as a guidance tool for intervention procedures.

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“…With the help of sensors, changes in Euler angles that occur during common movements performed by patients can be examined. With proper consideration given to the differences between experimental and computational methods [13], analyzing data using Euler angles can be a dependable approach for algorithms to effectively evaluate body position and movement. This enables accurate monitoring of patient conditions and allows for necessary adjustments to improve their comfort and overall well-being.…”

Section: Discussionmentioning

confidence: 99%

Evaluating the Feasibility of Euler Angles for Bed-Based Patient Movement Monitoring

Mayer,

Jose,

Kurgansky

et al. 2023

Signals

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In the field of modern healthcare, technology plays a crucial role in improving patient care and ensuring their safety. One area where advancements can still be made is in alert systems, which provide timely notifications to hospital staff about critical events involving patients. These early warning systems allow for swift responses and appropriate interventions when needed. A commonly used patient alert technology is nurse call systems, which empower patients to request assistance using bedside devices. Over time, these systems have evolved to include features such as call prioritization, integration with staff communication tools, and links to patient monitoring setups that can generate alerts based on vital signs. There is currently a shortage of smart systems that use sensors to inform healthcare workers about the activity levels of patients who are confined to their beds. Current systems mainly focus on alerting staff when patients become disconnected from monitoring machines. In this technical note, we discuss the potential of utilizing cost-effective sensors to monitor and evaluate typical movements made by hospitalized bed-bound patients. To improve the care provided to unaware patients further, healthcare professionals could benefit from implementing trigger alert systems that are based on detecting patient movements. Such systems would promptly notify mobile devices or nursing stations whenever a patient displays restlessness or leaves their bed urgently and requires medical attention.

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Addressing Discrepancies between Experimental and Computational Procedures

Cited by 6 publications

References 14 publications

Cushioning Effect of Conventional Padded Helmets on Interaction between Cerebrospinal Fluid and Brain after a Low-Speed Head Impact

Cushioning Effect of Conventional Padded Helmets on Interaction between Cerebrospinal Fluid and Brain after a Low-Speed Head Impact

Modeling Dynamics of the Cardiovascular System Using Fluid-Structure Interaction Methods

Evaluating the Feasibility of Euler Angles for Bed-Based Patient Movement Monitoring

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