2019
DOI: 10.21203/rs.2.10568/v1
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Addressing the drug resistant tuberculosis challenge through implementing a mixed model of care in Uganda, 2012- 2017

Abstract: Background Worldwide, Drug resistant Tuberculosis (DR-TB) remains a big problem; the diagnostic capacity has superseded the DR-TB clinical management capacity thereby causing ethical challenges. In Sub-Saharan Africa, treatment is either inadequate or lacking and some diagnosed patients are on treatment waiting lists. In Uganda, various health system challenges impeded scale up of DR-TB care in 2012; only three treatment initiation facilities existed, with only 41 of the estimated 1010 cases enrolled on treat… Show more

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“…Several factors are associated with DTT among children, and include among others, long treatment durations, high pill burden, medication-related side-effects, and symptom resolution. DTT thus remains a major obstacle to efficient TB control in developing countries like Uganda and has the potential to worsen the emergence of multi-drug resistant TB and death [9,10]. Some of the notable approaches to tackling DTT in children include the development of child-friendly policies, an integrated, family-based approach to TB care and services, addressing vulnerabilities faced by children with TB, providing support to their treatment supporters particularly women and the elderly, providing them with social protection, and promoting equitable access to child-friendly formulations of medicines to optimize treatment [11].…”
Section: Introductionmentioning
confidence: 99%
“…Several factors are associated with DTT among children, and include among others, long treatment durations, high pill burden, medication-related side-effects, and symptom resolution. DTT thus remains a major obstacle to efficient TB control in developing countries like Uganda and has the potential to worsen the emergence of multi-drug resistant TB and death [9,10]. Some of the notable approaches to tackling DTT in children include the development of child-friendly policies, an integrated, family-based approach to TB care and services, addressing vulnerabilities faced by children with TB, providing support to their treatment supporters particularly women and the elderly, providing them with social protection, and promoting equitable access to child-friendly formulations of medicines to optimize treatment [11].…”
Section: Introductionmentioning
confidence: 99%