Adenoid Basal Cell Carcinoma Simulating Ameloblastoma

Golda, Nicholas; Wheeland, Ronald G.

doi:10.1111/j.1524-4725.2009.01249.x

Cited by 4 publications

(5 citation statements)

References 14 publications

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“…Adenoid type of BCC is a rare histopathological variant which can morphologically present as pigmented and nonpigmented nodule or ulcer without any site predilection. Adenoid BCC has been reported at various sites including axillae, [5,8,11] back, [6,7,12] inner canthus of eye, [4,14] chin [9] and melolabial fold [10]. Akin to our case, the case reported by Jetley [13] had same location on the nose and both the cases revealed same histology of adenoid type of BCC (Table 1) [13].…”

Section: Discussionmentioning

confidence: 49%

“…Relevant resources were identified by a Pubmed/Medline search for databases from January 1950 to January 2016 using the keywords basal cell, carcinoma differentiation, adenoid, rare histopathological variant, and sunlight. A total of twelve papers were identified [4][5][6][7][8][9][10][11][12][13][14]. An attempt is made to document the histological features of adenoid variant of BCC in a 65-year-old male, who presented with a slow growing ulceroproliferative lesion on nose.…”

Section: Introductionmentioning

confidence: 99%

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Adenoid Basal Cell Carcinoma Presenting as Ulceroproliferative Nodule Nose: A Rare Histopathological Variant

Ralli¹

2018

BJSTR

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Section: Discussionmentioning

confidence: 49%

Section: Introductionmentioning

confidence: 99%

Adenoid Basal Cell Carcinoma Presenting as Ulceroproliferative Nodule Nose: A Rare Histopathological Variant

Ralli¹

2018

BJSTR

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“…It exact incidence is not known, but Patil, et al reported the incidence of 1.3% [4]. It is often regarded as a low grade malignancy compared to other subtypes like nodular and morpheic form [2], but has been reported to invade perivascular and perineural spaces in rare cases [6].…”

Section: Discussionmentioning

confidence: 99%

“…It can also show a tumor composed of thin cords of interconnected basaloid cells achieving a reticular or glandular-like pattern [5]. Occasional cells surrounding these gland-like lumina may have a secretory appearance [6].…”

Section: Discussionmentioning

confidence: 99%

Adenoid Variant of Basal Cell Carcinoma: A Case Report of a Rare Histopathological Subtype with Dermoscopic Aspects

Senhaji¹

2018

CDOAJ

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Basal cell carcinoma (BCC) is the most common cutaneous tumor, accounting for approximately 70% of all malignant diseases of the skin. Ultraviolet radiation is considered the single most important risk factor for BCC. Thus, it arises commonly on sun-exposed sites such as the head and neck. Adenoid subtype is one such rare, indolent variant of conventional BCC, with an incidence of 1.3%. It is often regarded as a low grade malignancy compared to other subtypes like nodular and morpheic form. We report here one such interesting very rare case of adenoid BCC of the malar region of the face with special regard to the dermoscopical and histological features.

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“…Morpheaform, infiltrating, and basosquamous BCCs have been associated with aggressive behaviors, including perineural invasion, whereas adenoid and adamantinoid BCCs are generally considered to be no more aggressive than nodular BCCs. Adenoid BCC shares histologic features with PA, and sometimes grows infiltratively into the deep subcutis, and thus, its differential diagnosis is obligatory 11,12. The present case of BCC occurred in the gingival epithelium and showed features of nodular, infiltrative, and adenoid patterns of tumor growth.…”

mentioning

confidence: 99%

Different Protein Expressions between Peripheral Ameloblastoma and Oral Basal Cell Carcinoma Occurred at the Same Mandibular Molar Area

Kim

Lee

2014

Korean J Pathol

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Peripheral ameloblastoma (PA) in gingiva is rare and often confused with oral basal cell carcinoma (OBCC). The tissues of one case of PA and one case of OBCC with the same mandibular molar area affected were compared via an immunohistochemical examination using 50 antisera. The PA and OBCC showed similar proliferation of basaloid epithelial strands, but toluidine blue staining revealed that the PA had pinkish juxta-epithelial myxoid tissue, whereas the OBCC was infiltrated by many mast cells. Immunohistochemical comparisons showed that the PA was strongly positive for ameloblastin, KL1, p63, carcinoembryonic antigen, focal adhesion kinase, and cathepsin K, and slightly positive for amelogenin, Krox-25, E-cadherin, and PTCH1, whereas the OBCC was not. On the other hand, the OBCC was strongly positive for EpCam, matrix metalloprotease (MMP)-1, α1-antitrypsin, cytokeratin-7, p53, survivin, pAKT1, transforming growth factor-β1, NRAS, TGase-1, and tumor nescrosis factor-α, and consistently positive for β-catenin, MMP-2, cathepsin G, TGase-2, SOS-1, sonic hedgehog, and the β-defensins-1, -2, -3, while the PA was not. These data suggest that the tumorigeneses of PA and OBCC differ, and that PAs undergo odontogenic differentiation and generate oncogenic signals for infiltrative growth and bone resorption, whereas OBCCs undergo basaloid epidermal differentiation as a result of growth factor/cytokine-related oncogenic signals.

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Adenoid Basal Cell Carcinoma Simulating Ameloblastoma

Cited by 4 publications

References 14 publications

Adenoid Basal Cell Carcinoma Presenting as Ulceroproliferative Nodule Nose: A Rare Histopathological Variant

Adenoid Basal Cell Carcinoma Presenting as Ulceroproliferative Nodule Nose: A Rare Histopathological Variant

Adenoid Variant of Basal Cell Carcinoma: A Case Report of a Rare Histopathological Subtype with Dermoscopic Aspects

Different Protein Expressions between Peripheral Ameloblastoma and Oral Basal Cell Carcinoma Occurred at the Same Mandibular Molar Area

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