Adenomas paratiroideos de localización intratiroidea: derechos y bajos

Ros, Susana; Sitges‐Serra, Antonio; Pereira, José António; Jimeno, Jaime; Prieto, Rosa; Sancho, Juan José Alegre; Pérez-Ruiz, L

doi:10.1016/s0009-739x(08)72619-8

Cited by 23 publications

(6 citation statements)

References 12 publications

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“…[12] In a recent study, localization of most of the adenomas (70.6%) was shown to be on the right side and on the lower third of the thyroid lobes. [13] This study also reported that intrathyroidal parathyroid adenomas were present in 3% of patients submitted for parathyroidectomy. [13] However, reports of a giant intrathyroidal parathyroid adenoma in the literature are exceptional.…”

Section: Discussionmentioning

confidence: 74%

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Giant intrathyroidal parathyroid adenoma

Vilallonga

Zafón

Migone

et al. 2012

J Emerg Trauma Shock

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Primary hyperparathyroidism (PHPT) is not an uncommon endocrine disorder. However, acute primary hyperparathyroidism, or parathyroid crisis (PC), is a rare clinical entity characterized by life-threatening hypercalcemia of a sudden onset in patients with PHPT. We describe a patient with PC who presented with acute worsening of depressive symptoms, nausea and vomiting, and required emergency surgery. Serum calcium, alkaline phosphatase, and parathyroid hormone were elevated and serum phosphorus was low. An emergency hemithyroidectomy was performed because of none medical control of hypercalcemia. A giant intrathyroidal parathyroid adenoma was diagnosed. PHTP can be a life-threatening situation for patients, requiring immediate surgical treatment. A giant intrathyroidal parathyroid adenoma is an uncommon cause of PC.

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Section: Discussionmentioning

confidence: 74%

“…[13] This study also reported that intrathyroidal parathyroid adenomas were present in 3% of patients submitted for parathyroidectomy. [13] However, reports of a giant intrathyroidal parathyroid adenoma in the literature are exceptional. [14]…”

Section: Discussionmentioning

confidence: 74%

Giant intrathyroidal parathyroid adenoma

Vilallonga

Zafón

Migone

et al. 2012

J Emerg Trauma Shock

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“…[8] The incidence of ETPG has been reported in the literature to range from 0.7% to 3.4%, and 70.6% occur in the right lobe of the thyroid gland, with a prevalence in the lower extreme 1/3. [3,4] Six parathyroids were ectopic in the thyroid gland in the 5 patients with ETPG in this study, including one in the upper pole of the left thyroid, one in the lower pole of the left thyroid, one in the middle and lower poles of the left thyroid, one in the middle and upper pole of the right thyroid, one in the lower pole of the right thyroid, and one in the middle part of the right thyroid, which may be related to the rarity of the disease and the small sample size of the present study.…”

Section: Discussionmentioning

confidence: 99%

The value of ultrasound in combination with 99mTc-MIBI imaging department of ultrasound medicine, for the diagnosis of ectopic parathyroid glands in the thyroid gland in patients with secondary hyperparathyroidism

Zhao,

Chen,

Zang

et al. 2024

Medicine

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To investigate the value of preoperative ultrasound combined with 99mTc-MIBI imaging for the diagnosis of ectopic intrathyroid parathyroid gland (ETPG) in patients with secondary hyperparathyroidism (SHPT). One hundred and eleven patients with SHPT who underwent total parathyroidectomy plus forearm transplantation from January 2015 to January 2022 in the Third Hospital of Hebei Medical University were selected. All patients underwent routine preoperative ultrasonography and 99mTc-MIBI imaging, and with pathological diagnosis as the gold standard, the clinical data of ETPG patients were selected, including clinical manifestations, laboratory tests, preoperative ultrasonography and 99mTc-MIBI imaging for localization and diagnosis, intraoperative exploration and postoperative pathology, and postoperative follow-up. To analyze the ultrasound manifestations of preoperative parathyroid hyperplasia and the results of 99mTc-MIBI imaging in patients with ETPG. Among 111 patients with SHPT, there were 5 patients with ETPG, 1 male and 4 females with a mean age of (45.00 ± 5.05) years, and 6 ectopic parathyroid glands were located in the thyroid gland. The incidence of ETPG was 4.5% (5/111), 4 were detected by ultrasound, 2 were not detected with a diagnostic accuracy of 66.7% (4/6), 3 were positive for 99mTc-MIBI imaging, 3 were negative with a diagnostic accuracy of 50.0% (3/6). Among them, one was not detected by ultrasound, but was positive for 99mTc-MIBI imaging, 2 with negative 99mTc-MIBI imaging, but all were detected by ultrasound, and one with negative 99mTc-MIBI imaging was detected by ultrasound but misdiagnosed as a thyroid nodule. A total of 5 ETPGs were detected by ultrasound combined with 99mTc-MIBI imaging, with a diagnostic accuracy of 83.3% (5/6). Patients’ postoperative serum calcium and serum parathyroid hormone (PTH) levels were normalized or significantly decreased from preoperative levels. Ultrasound combined with 99mTc-MIBI imaging can achieve higher accuracy than either examination alone in the preoperative localization and diagnosis of ETPG in SHPT patients.

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“…Central thyroid and its fusion with the lateral portions, although another theory postulates an excessive descent in the inferior migration of the IV brachial arch, being the most frequent location being the lower right. 4,5 Intrathyroid parathyroid adenomas are the second leading cause of persistent hyperparathyroidism after intrathymic adenomas, with a reported incidence between 1.3 to 6.7. 4,5 Diagnostic precision and preoperative location are important because they affect surgical behavior.…”

Section: Discussionmentioning

confidence: 99%

“…4,5 Intrathyroid parathyroid adenomas are the second leading cause of persistent hyperparathyroidism after intrathymic adenomas, with a reported incidence between 1.3 to 6.7. 4,5 Diagnostic precision and preoperative location are important because they affect surgical behavior. Scintigraphy technetium (TC) 99m scan with single proton emission tomography (sestamibi SPECT) has a high sensitivity for the diagnosis of intrathyroid parathyroid lesions and is the main method of localization, however it does not have adequate specificity and its ability to identify anatomy is not the ideal.…”

Section: Discussionmentioning

confidence: 99%

Intrathyroid parathyroid adenoma: report of two cases and literature review

Pinzon¹,

Valencia²,

Condoy³

et al. 2020

Int J Res Med Sci

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Approximately 80% of patients with primary hyperparathyroidism have a parathyroid adenoma, with surgery being the only definitive treatment. Sometimes in surgery there is difficulty in identifying the pathological parathyroid gland at which time the possibility of ectopic parathyroid should be considered. We present two cases of patients which after hemithyroidectomy histopathological report, reported intrathyroid parathyroid adenoma. Intrathyroid parathyroid adenomas are an infrequent presentation of parathyroid adenomas that require high clinical suspicion if they are not detected by imaging studies in the preoperative period.

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Adenomas paratiroideos de localización intratiroidea: derechos y bajos

Cited by 23 publications

References 12 publications

Giant intrathyroidal parathyroid adenoma

Giant intrathyroidal parathyroid adenoma

The value of ultrasound in combination with 99mTc-MIBI imaging department of ultrasound medicine, for the diagnosis of ectopic parathyroid glands in the thyroid gland in patients with secondary hyperparathyroidism

Intrathyroid parathyroid adenoma: report of two cases and literature review

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