Adherence to Asthma Regimens

Creer, Thomas L.; Levstek, Deirdre

doi:10.1007/978-1-4899-1760-7_7

Cited by 3 publications

(1 citation statement)

References 41 publications

(35 reference statements)

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“…However, researchers report that patient nonadherence to inhaled corticosteroids and other preventive asthma therapies is often more than 50% (Creer, 1993;Jerome, Wigal, & Creer, 1987;Rand & Wise, 1996). Although there is no generally recognized minimum adherence rate that would ensure clinical benefit, 80% to 85% adherence has been used as a benchmark (Creer & Levstek, 1997).…”

Section: Problemmentioning

confidence: 99%

Promoting Adherence

Schaffer

Tian

2004

Clin Nurs Res

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This study compared the effects of a theoretically focused audiotape and a standard educational booklet on asthma preventive medication adherence and other asthma outcomes. Forty-six adult asthmatics were randomly assigned to receive either an experimental audiotape incorporating components of protection motivation theory, a standard asthma management booklet, both, or no educational materials. Outcomes were assessed at baseline, 3 months, and 6 months. Mean pharmacy-verified adherence improved 15% to 19% in the intervention groups and declined 22% in the control group at 6 months. Using analysis of covariance (ANCOVA) to control for baseline adherence, these changes were significant between the control and booklet group (t = 2.47; p = .02) and between control and combined group (t = 2.07; p = .04). Providing a minimal educational intervention can have a beneficial effect on asthma medication adherence that persists at least 6 months.

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Section: Problemmentioning

confidence: 99%

Promoting Adherence

Schaffer

Tian

2004

Clin Nurs Res

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Childhood Asthma

Creer¹

1998

Handbook of Child Psychopathology

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A data-driven typology of asthma medication adherence using cluster analysis

Tibble

Chan

Mitchell

et al. 2020

Sci Rep

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Asthma preventer medication non-adherence is strongly associated with poor asthma control. One-dimensional measures of adherence may ignore clinically important patterns of medication-taking behavior. We sought to construct a data-driven multi-dimensional typology of medication non-adherence in children with asthma. We analyzed data from an intervention study of electronic inhaler monitoring devices, comprising 211 patients yielding 35,161 person-days of data. Five adherence measures were extracted: the percentage of doses taken, the percentage of days on which zero doses were taken, the percentage of days on which both doses were taken, the number of treatment intermissions per 100 study days, and the duration of treatment intermissions per 100 study days. We applied principal component analysis on the measures and subsequently applied k-means to determine cluster membership. Decision trees identified the measure that could predict cluster assignment with the highest accuracy, increasing interpretability and increasing clinical utility. We demonstrate the use of adherence measures towards a three-group categorization of medication non-adherence, which succinctly describes the diversity of patient medication taking patterns in asthma. The percentage of prescribed doses taken during the study contributed to the prediction of cluster assignment most accurately (84% in out-of-sample data).

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Adherence to Asthma Regimens

Cited by 3 publications

References 41 publications

Promoting Adherence

Promoting Adherence

Childhood Asthma

A data-driven typology of asthma medication adherence using cluster analysis

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