Adherence to New CDC Chlamydia Treatment Guidelines in Adolescents: Effective Uptake and Equitable Implementation

Makeneni, Spandana; Wood, Sarah

doi:10.1089/apc.2022.0190

Cited by 2 publications

(3 citation statements)

References 11 publications

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“…12 They found that the proportion of CT cases prescribed doxycycline increased substantially from 6% (2019) and 9% (2020) to 54% in 2021 after the implementation of the updated CDC treatment guidelines. 12 This highlights the potential for a rapid shift in prescribing practices among clinics that were predominately prescribing azithromycin before the guidelines change. More analyses are needed to evaluate the implementation of the guidelines change, including understanding which facility types are less likely to adhere to the new guidelines and what are the characteristics of cases that continue to receive azithromycin.…”

Section: Discussionmentioning

confidence: 99%

“…Second, a recent study conducted in mid-Atlantic pediatric primary care clinics suggests that there have been some shifts in CT prescribing practices already. In that study, the authors analyzed the impact of the 2021 guideline change on CT prescribing practices using electronic health records in 2 years before the guidelines change and the 6 months after the guideline change 12 . They found that the proportion of CT cases prescribed doxycycline increased substantially from 6% (2019) and 9% (2020) to 54% in 2021 after the implementation of the updated CDC treatment guidelines 12 .…”

Section: Discussionmentioning

confidence: 99%

“…In that study, the authors analyzed the impact of the 2021 guideline change on CT prescribing practices using electronic health records in 2 years before the guidelines change and the 6 months after the guideline change 12 . They found that the proportion of CT cases prescribed doxycycline increased substantially from 6% (2019) and 9% (2020) to 54% in 2021 after the implementation of the updated CDC treatment guidelines 12 . This highlights the potential for a rapid shift in prescribing practices among clinics that were predominately prescribing azithromycin before the guidelines change.…”

Section: Discussionmentioning

confidence: 99%

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Trends in Chlamydia trachomatis Treatment Prescribing Practices in King County, Washington, 2010–2018

Brase,

Dombrowski,

Berzkalns

et al. 2024

Sexual Trans Dis

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Background In 2021, national Chlamydia trachomatis (CT) treatment guidelines changed from recommending either azithromycin (1 gram; single dose) or doxycycline (100 mg twice daily for 7 days) to recommending only doxycycline as first-line treatment. The distribution and trends in CT prescribing practices prior to the guidelines change is largely unknown. Methods We conducted a trends analysis using Washington STD surveillance data. We included all female cases of urogenital CT aged >15 years who resided in King County and were diagnosed between 2010 and 2018. Surveillance data included information on demographics, sexual history, clinical features, diagnosing facility (e.g., emergency department, family planning), and treatment regimen. We conducted descriptive analyses to examine trends in prescribing practices over time and by facility type. We used Poisson regression to examine the association between CT case characteristics and receipt of receipt of azithromycin. Results There were 36,830 cases of female urogenital CT during the study period. The percent of cases receiving azithromycin increased significantly from 86% in 2010 to 94% in 2018; the percent receiving doxycycline decreased from 13% to 5%. Five of the eight facility types prescribed azithromycin to >95% of CT cases by 2018. Cases who were younger or cases of color were more likely to receive azithromycin (versus doxycycline) compared to older and White cases respectively. Conclusions A substantial shift in CT prescribing practices will be needed to adhere to new CT treatment guidelines. Our findings highlight the need for targeted provider education and training to encourage the transition to doxycycline use.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Trends in Chlamydia trachomatis Treatment Prescribing Practices in King County, Washington, 2010–2018

Brase,

Dombrowski,

Berzkalns

et al. 2024

Sexual Trans Dis

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Providing adolescent-friendly sexually transmitted infection screening and treatment services

Friedman,

Cannon,

Tyson

et al. 2024

Current Opinion in Obstetrics &Amp; Gynecology

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Purpose of review There are high rates of sexually transmitted infections (STIs) worldwide. Adolescents and young adults (AYA) ages 15–24 years remain one of the populations that is most vulnerable to STIs. The goal of this review is to summarize recent international updates in adolescent STI screening and treatment. Recent findings Normalizing sexual history taking and STI testing, and advocating for adolescents to receive comprehensive sexuality education improves stigma surrounding sexual health. The global rise in syphilis is pervasive and includes high rates of infection among AYA and women of reproductive age – universal screening may be indicated depending on local epidemiology. Gonococcal antimicrobial resistance remains a significant public health concern worldwide, thus judicious use of antimicrobials and reporting cases of resistance is crucial. Sexual health services are increasingly using virtual platforms, which may be an effective strategy for STI testing and treatment among AYA. Summary Specific areas of focus to address the STI epidemic among AYA include reducing stigma surrounding sexual health, screening, and treatment of STIs, especially with the global rise in syphilis and high rates of gonorrhea resistance, in addition to increased use of telehealth services as effective education and intervention strategies.

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Adherence to New CDC Chlamydia Treatment Guidelines in Adolescents: Effective Uptake and Equitable Implementation

Cited by 2 publications

References 11 publications

Trends in Chlamydia trachomatis Treatment Prescribing Practices in King County, Washington, 2010–2018

Trends in Chlamydia trachomatis Treatment Prescribing Practices in King County, Washington, 2010–2018

Providing adolescent-friendly sexually transmitted infection screening and treatment services

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