Adipose tissue: Another target organ for lead accumulation? A study on sardinian children (Italy)

Vallascas, Elisabetta; Micco, Alessandro De; Deiana, Fabrizio; Banni, Sebastiano; Sanna, Emanuele

doi:10.1002/ajhb.22448

Cited by 12 publications

(7 citation statements)

References 76 publications

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“…Sanna et al (2011) reported lower levels of hair Pb also in eastern Sardinia. Vallascas et al (2013) reported mean values of Pb in hair of 3.65 μg g À 1 in males and 2.98 μg/g in females for 11-15 year old boys and girls of central-southern Sardinia, sampled from 1998 to 2007.…”

Section: Qmeqas08h-02mentioning

confidence: 98%

Metals and metalloids in hair samples of children living near the abandoned mine sites of Sulcis-Inglesiente (Sardinia, Italy)

Varrica¹,

Tamburo²,

Milia³

et al. 2014

Environmental Research

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Section: Qmeqas08h-02mentioning

confidence: 98%

Metals and metalloids in hair samples of children living near the abandoned mine sites of Sulcis-Inglesiente (Sardinia, Italy)

Varrica¹,

Tamburo²,

Milia³

et al. 2014

Environmental Research

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“…Due to the toxicity of lead (Pb) compounds, its intake from food is one of the riskiest [46,63]. The most common source of Pb exposure for humans is the ingestion of contaminated food and drinking water [46,[63][64][65].…”

Section: Chemical and Toxicological Aproperties Of Selected Contaminantsmentioning

confidence: 99%

The Monitoring of Selected Heavy Metals Content and Bioavailability in the Soil-Plant System and Its Impact on Sustainability in Agribusiness Food Chains

2021

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This study assisted in identifying and preventing the increase in heavy metals in soil and winter wheat. Its accumulation can affect cultivated crops, quality and crop yields, and consumers’ health. Selected heavy metals were analyzed using the GTAAS method. They were undertaken on selected heavy metals content (Cd, Cu, Pb, and Zn) in arable soils at three sites in Slovakia and their accumulation in parts of cultivated winter wheat. Our study showed that the limit value of Cd in soil samples was exceeded in the monitored arable soils from 2017–2019. The average content values of Cu and Zn did not exceed the limit values, even in Pb values (except for the spring period). The analyses also showed that the heavy metals content for plants bioavailable in soil did not exceed the statutory critical values for Cd, Cu, and Zn’s average content values. However, Pb content exceeded permitted critical values. Heavy metals bioaccumulation (Zn, Cu) was within the limit values in wheat. Analyzed Cd content in wheat roots and Pb content were determined in all parts of wheat except grain. The study showed that grain from cultivated winter wheat in monitored arable soils is not a risk for consumers.

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“…However, exposure to higher concentrations through oral ingestion, dermal contact or inhalation can be toxic for human health ( 3 ). Some heavy metals accumulate in the body and are stored in various tissues, including the adipose tissue ( 5 ). They can also be found in hair ( 6 , 7 ).…”

Section: Introductionmentioning

confidence: 99%

Excretion of Heavy Metals and Glyphosate in Urine and Hair Before and After Long-Term Fasting in Humans

et al. 2021

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Background: Dietary exposure to environmental pollutants in humans is an important public health concern. While long-term fasting interrupts the dietary exposure to these substances, fat mobilization as an energy source may also release bioaccumulated substances. This was, to our knowledge, only investigated in obese people decades ago. This study explored the effects of 10-days fasting on the excretion of heavy metals and glyphosate.Methods: Urinary levels of arsenic, chromium, cobalt, lead, nickel, mercury and glyphosate were measured before and after 10 fasting days in 109 healthy subjects. Additionally, hair analysis was done before and ten weeks after fasting in 22 subjects.Results: Fasting caused a decrease in body weight, and in urinary arsenic (by 72%) and nickel (by 15%) concentrations. A decrease in lead hair concentrations (by 30%) was documented. Urinary mercury levels were unchanged for chromium, cobalt and glyphosate, which were undetectable in most of the subjects. Additionally, fatigue, sleep disorders, headache and hunger were reduced. Body discomfort symptoms diminished four weeks after food reintroduction.Conclusions: The results of this study provide the first insights into the changes in heavy metal excretion caused by long-term fasting. Further studies focusing on the kinetics of efflux between different compartments of the body are needed.Clinical Trial Registration:https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00016657, identifier: DRKS00016657.

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Adipose tissue: Another target organ for lead accumulation? A study on sardinian children (Italy)

Cited by 12 publications

References 76 publications

Metals and metalloids in hair samples of children living near the abandoned mine sites of Sulcis-Inglesiente (Sardinia, Italy)

Metals and metalloids in hair samples of children living near the abandoned mine sites of Sulcis-Inglesiente (Sardinia, Italy)

The Monitoring of Selected Heavy Metals Content and Bioavailability in the Soil-Plant System and Its Impact on Sustainability in Agribusiness Food Chains

Excretion of Heavy Metals and Glyphosate in Urine and Hair Before and After Long-Term Fasting in Humans

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