Adjuvant Ovarian Function Suppression in Premenopausal Hormone Receptor–Positive Breast Cancer
Robert B. Basmadjian,
Sasha Lupichuk,
Yuan Xu
et al.
Abstract:ImportanceFew oncology studies have assessed the effectiveness of adjuvant ovarian function suppression (OFS) in observational settings for premenopausal hormone receptor–positive breast cancer. Target trial emulation is increasingly used for estimating treatment outcomes in observational cohorts.ObjectivesTo describe hormone therapy and OFS treatment patterns (aim 1), examine the association between adding OFS to tamoxifen (TAM) or aromatase inhibitor (AI) and survival (aim 2), and examine the association bet… Show more
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