Adult farming exposure does not protect against sensitization to the storage mite Lepidoglyphus destructor

Elholm, Grethe; Schlünssen, Vivi; Doekes, Gert; Basinas, Ioannis; Omland, Øyvind; Grønager, Pernille Milvang; Sigsgaard, Torben

doi:10.1111/all.13533

Cited by 7 publications

(11 citation statements)

References 13 publications

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“…18 The prevalence of storage mite sensitization in the present study as well as in the studies from Reykjavik and on allergic outpatients referred to above is lower compared to storage mite sensitization reported for bakers in Bergen (14% with SPT positivity) as well as among farmers in Denmark (14%, L destructor). 5,25 This suggests that occupational exposure may be an important factor for storage mite sensitization. However, in this study, we did not identify a single person with storage mite sensitization in occupations related to higher exposure to storage mites.…”

Section: Discussionmentioning

confidence: 99%

“…In a group of 1100 Danish farmers, the sensitization to L destructor increased from 6% to 13% over 12 years. 12 In a study on bakers in Norway, storage mite sensitization was verified among 20% of the study participants. 5 In Danish, bakers' apprentices sensitization to HDM and storage mites were 18% and 11%, respectively.…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore , it has recently been shown that the general tendency to lower sensitization rates in farmers does not apply for storage mites. In a group of 1100 Danish farmers, the sensitization to L destructor increased from 6% to 13% over 12 years …”

Section: Introductionmentioning

confidence: 99%

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Prevalence of allergic sensitization to storage mites in Northern Europe

Jõgi

Olsen

Svanes

et al. 2019

Clin Experimental Allergy

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Background Allergic sensitization to storage mites has mostly been related to occupational exposures like farming, grain/cattle handling, whereas for non‐occupational settings, storage mite sensitization has been attributed to cross‐reactivity with house dust mite (HDM) allergens. Objective We aimed to describe the prevalence of allergic sensitization to storage mites, co‐sensitization to HDM allergens and respiratory symptoms in Denmark, Iceland, Norway and Sweden. Methods The population comprised of 1180 participants born 1945‐1972 of the third follow‐up of the population‐based cohort European Community Respiratory Health Survey (ECRHS) in Aarhus, Bergen, Reykjavik and Uppsala. A clinical examination included skin prick tests (SPT) to Lepidoglyphus destructor, Tyrophagus putrescentiae, Acarus siro and common inhalant allergens, as well as standardized interviews. Results 8% were sensitized to HDM and 10% to storage mite, with some variation by study centre: Reykjavik 13%, Bergen 8% and Aarhus 7%. In Uppsala, only L destructor (3%) was measured. Storage mite sensitization was higher among men (11%) than women (8%). Among storage mite sensitized, 44% were also sensitized to HDM. Storage mite sensitization was associated with asthma and nasal allergies, but not with age, education, pet keeping or place of upbringing. Conclusions and Clinical Relevance In this Northern European population‐based study, allergic sensitization to storage mite was as common as HDM sensitization. Storage mite sensitization was, independently of HDM sensitization, associated with respiratory symptoms and asthma. Our findings suggest that storage mite sensitization should be evaluated with regard to inclusion into the common inhalant allergen panel in Northern Europe.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Prevalence of allergic sensitization to storage mites in Northern Europe

Jõgi

Olsen

Svanes

et al. 2019

Clin Experimental Allergy

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“…Respiratory allergy refers to the presence of respiratory allergic disease (rhinitis and asthma) and a positive skin prick test (SPT) reaction or presence of specific IgE [28]. Sensitization or atopy is performed by skin prick test (SPT), showing one or more positive reactions (wheal diameter ≥ 3 mm) to tested allergens and positive (histamine) and negative (saline) controls [27,28,32,34,37]. Respiratory function is tested for each subject with respiratory symptoms (FEV1/FEV6; FEV1/FVC.…”

Section: Discussionmentioning

confidence: 99%

“…The farm work-specific allergens included storage mites Acarus siro, Lepidoglyphus destructor, Tyrophagus putrescentiae, cow epithelium, pig epithelium, horse epithelium and hay, grain and straw dust [34]. Storage mites, specifically Lepidoglyphus, are a typical occupational allergen, for which new sensitization might occur in the first years of a farmers worklife [37] Among swine breeders, high infestation rates of D. farinae and Aeroglyphus robustus in reproductive status and a low to medium presence of Lepidoglyphus destructor, Deuteronymph, Cheyletus eruditus, and Euroglyphus maynei in vital status were found. Among molds and pollens, the mean concentrations of Alternaria, Cladosporium, Fusarium, Epicoccum, Torula, Helminthosporium, Stemphylium, Plantago and Parietaria species were higher outside the farm than inside the pig farms, with intermediate values for inside farms without pigs [28].…”

Section: Allergensmentioning

confidence: 99%

Allergic Anaphylactic Risk in Farming Activities: A Systematic Review

Arcangeli

Traversini

Tomasini

et al. 2020

IJERPH

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Allergic disorders in the agriculture sector are very common among farm workers, causing many injuries and occupational diseases every year. Agricultural employees are exposed to multiple conditions and various allergenic substances, which could be related to onset of anaphylactic reactions. This systematic review highlights the main clinical manifestation, the allergens that are mostly involved and the main activities that are usually involved. This research includes articles published on the major databases (PubMed, Cochrane Library, Scopus), using a combination of keywords. The online search yielded 489 references; after selection, by the authors, 36 articles (nine reviews and 27 original articles) were analyzed. From this analysis, the main clinical problems that were diagnosed in this category were respiratory (ranging from rhinitis to asthma) and dermatological (eczema, dermatitis, hives) in nature, with a wide symptomatology (from a simple local reaction to anaphylaxis). The main activities associated with these allergic conditions are harvesting or cultivation of fruit and cereals, beekeepers and people working in greenhouses. Finally, in addition to the allergens already known, new ones have emerged, including triticale, wine, spider and biological dust. For these reasons, in the agricultural sector, research needs to be amplified, considering new sectors, new technologies and new products, and ensuring a system of prevention to reduce this risk.

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