Advanced fabrication process for combined atomic force-scanning electrochemical microscopy (AFM-SECM) probes

Eifert, Alexander; Mizaikoff, Boris; Kranz, Christine

doi:10.1016/j.micron.2014.08.008

Cited by 35 publications

(25 citation statements)

References 45 publications

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“…Combination of AFM with SECM is by nature very powerful, taking advantage of micro/nanofabrication techniques to tune the electrode shape and size [18][19][20][21]. By comparison, the simplicity of fabrication of SICM probes makes them very successful for laboratory experiment at the interface with living materials [14,22].…”

Section: Introductionmentioning

confidence: 99%

Shearforce positioning of nanoprobe electrode arrays for scanning electrochemical microscopy experiments

Adam

Kanoufi

Šojić

et al. 2015

Electrochimica Acta

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Section: Introductionmentioning

confidence: 99%

Shearforce positioning of nanoprobe electrode arrays for scanning electrochemical microscopy experiments

Adam

Kanoufi

Šojić

et al. 2015

Electrochimica Acta

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“…Single carbon nanotubes were attached to an AFM cantilever and used as electrodes 58 . Various fabrications for commercial pyramidal AFM have been developed through metal deposition, and finer‐sized tips can be obtained through focused ion beam (FIB) milling 59 …”

Section: Nanoelectrodementioning

confidence: 99%

Bioanalytical chemistry with scanning electrochemical microscopy

Gwon

Lim

Ahn

2021

Bulletin Korean Chem Soc

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Scanning electrochemical microscopy (SECM) is a powerful and suitable tool for visualizing local electrochemical activity as well as topography of surfaces. Due to the development of electrode manufacturing technology, high spatial resolution can be achieved, and various applications are possible by combining SECM with other technologies. Many studies have applied SECM to bioanalytical chemistry at the single‐cell level. The purpose of this review is to introduce various advanced nanoelectrode fabrication techniques and their subsequent applications in bioanalytical research using SECM.

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“…Compared with SICM, the combination with AFM not only creates excellent spatial resolution, it also provides synchronous nanoscale measurements of topographical changes and mechanical information on the specimen [73]. Several methods have been reported for fabricating AFM-SECM probes, including etching and insulating conductive microwires (Au or Pt) [74], plasma-enhanced chemical vapor deposition [75], and FIB milling [76]. The high spatial and topographical resolution of the AFM analyses coupled with the amperometric information obtained from an SECM section make AFM-SECM a reliable tool for studying complex live biological samples such as DNA chains and protein distributions [77].…”

Section: Instrumentation and Operating Modesmentioning

confidence: 99%

Recent Advances in Scanning Electrochemical Microscopy for Biological Applications

Huang

Lou

et al. 2018

Materials

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Scanning electrochemical microscopy (SECM) is a chemical microscopy technique with high spatial resolution for imaging sample topography and mapping specific chemical species in liquid environments. With the development of smaller, more sensitive ultramicroelectrodes (UMEs) and more precise computer-controlled measurements, SECM has been widely used to study biological systems over the past three decades. Recent methodological breakthroughs have popularized SECM as a tool for investigating molecular-level chemical reactions. The most common applications include monitoring and analyzing the biological processes associated with enzymatic activity and DNA, and the physiological activity of living cells and other microorganisms. The present article first introduces the basic principles of SECM, followed by an updated review of the applications of SECM in biological studies on enzymes, DNA, proteins, and living cells. Particularly, the potential of SECM for investigating bacterial and biofilm activities is discussed.

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Advanced fabrication process for combined atomic force-scanning electrochemical microscopy (AFM-SECM) probes

Cited by 35 publications

References 45 publications

Shearforce positioning of nanoprobe electrode arrays for scanning electrochemical microscopy experiments

Shearforce positioning of nanoprobe electrode arrays for scanning electrochemical microscopy experiments

Bioanalytical chemistry with scanning electrochemical microscopy

Recent Advances in Scanning Electrochemical Microscopy for Biological Applications

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