Advanced materials for optical sensing and biosensing of neurotransmitters

Soleymani, Jafar

doi:10.1016/j.trac.2015.03.017

Cited by 36 publications

(29 citation statements)

References 128 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The selective and sensitive determination of biomolecules is of high importance to biomedical studies, disease diagnosis, and drug screening . Therefore, a number of determination methods for biomolecules exploiting several principles of detection have been developed, such as electroanalytical sensors , chromatographic analysis , label‐free fluorescence based method , UV‐visible absorption spectroscopy , colorimetric analytical methods , piezoelectric methods , surface enhanced Raman scattering spectroscopy , and eletrochemiluminescence based sensors .…”

Section: Introductionsupporting

confidence: 60%

Photoelectroanalytical Sensor Based on TiO₂ Nanoparticles/Copper Tetrasulfonated Phthalocyanine for Detection of Dopamine Exploiting Light Emitting Diode Irradiation

2016

View full text Add to dashboard Cite

In this manuscript, a novel photoelectroanalytical sensor for detection of dopamine based on anatase TiO2 nanoparticles sensitized with copper tetrasulfonated phthalocyanine (CuTsPc/TiO2) was developed. The CuTsPc/TiO2 photoelectroanalytical sensor shows high anodic photocurrent under visible light emitting diode irradiation in comparison to pure anatase TiO2 nanoparticles. The CuTsPc/TiO2 composite shows a photocurrent about 2.5‐fold higher than those of pure TiO2 nanoparticles or CuTsPc modified electrode. The CuTsPc/TiO2 composite shows a low charge transfer resistance in comparison to its individual components as well as the impedance circle radius decreases significantly under UV light illumination. Under optimized conditions, the photoelectroanalytical sensor shows a linear response range from 4 up to 810 µmol L−1 with a sensitivity of 3.0 nA L µmol−1 and limit of detection of 0.5 µmol L−1 for the detection of dopamine. The photoelectrochemical sensor shows high photocurrent to dopamine in comparison to foreign species such as ascorbic acid, uric acid, glucose, K+, Na+, and Cl−.

show abstract

Section: Introductionsupporting

confidence: 60%

Photoelectroanalytical Sensor Based on TiO₂ Nanoparticles/Copper Tetrasulfonated Phthalocyanine for Detection of Dopamine Exploiting Light Emitting Diode Irradiation

2016

View full text Add to dashboard Cite

show abstract

“…DA is classified as monoamine. DA is an important and special NT that possesses both properties, and plays many critical roles in human health related to the central nervous, renal, cardiovascular, and hormonal systems, and other animals including both vertebrates and invertebrates [1][2][3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

“…many critical roles in human health related to the central nervous, renal, cardiovascular, and hormonal systems, and other animals including both vertebrates and invertebrates [1][2][3][4][5][6]. In the late 1950s, DA was discovered to be a NT by Arvid Carlsson [7,8].…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Eddin

Fen

2020

Sensors

View full text Add to dashboard Cite

Nowadays, several neurological disorders and neurocrine tumours are associated with dopamine (DA) concentrations in various biological fluids. Highly accurate and ultrasensitive detection of DA levels in different biological samples in real-time can change and improve the quality of a patient’s life in addition to reducing the treatment cost. Therefore, the design and development of diagnostic tool for in vivo and in vitro monitoring of DA is of considerable clinical and pharmacological importance. In recent decades, a large number of techniques have been established for DA detection, including chromatography coupled to mass spectrometry, spectroscopic approaches, and electrochemical (EC) methods. These methods are effective, but most of them still have some drawbacks such as consuming time, effort, and money. Added to that, sometimes they need complex procedures to obtain good sensitivity and suffer from low selectivity due to interference from other biological species such as uric acid (UA) and ascorbic acid (AA). Advanced materials can offer remarkable opportunities to overcome drawbacks in conventional DA sensors. This review aims to explain challenges related to DA detection using different techniques, and to summarize and highlight recent advancements in materials used and approaches applied for several sensor surface modification for the monitoring of DA. Also, it focuses on the analytical features of the EC and optical-based sensing techniques available.

show abstract

“…In terms of in vivo sensing of neurotransmitters, another popular and promising sensing technique besides electrochemical methods is the optical detection approaches. In most cases, optical sensors exhibit highly reproducible and sensitive readings with the limit of detection often reaching a nanomolar range or less [130]. Also, the interference from other chemical species could be minimized by utilizing a broad range of optical spectrum.…”

Section: Optical Sensing Of Neurotransmittersmentioning

confidence: 99%

Recent Advances in the Detection of Neurotransmitters

Song

2018

Chemosensors

155

View full text Add to dashboard Cite

Neurotransmitters are chemicals that act as messengers in the synaptic transmission process. They are essential for human health and any imbalance in their activities can cause serious mental disorders such as Parkinson's disease, schizophrenia, and Alzheimer's disease. Hence, monitoring the concentrations of various neurotransmitters is of great importance in studying and diagnosing such mental illnesses. Recently, many researchers have explored the use of unique materials for developing biosensors for both in vivo and ex vivo neurotransmitter detection. A combination of nanomaterials, polymers, and biomolecules were incorporated to implement such sensor devices. For in vivo detection, electrochemical sensing has been commonly applied, with fast-scan cyclic voltammetry being the most promising technique to date, due to the advantages such as easy miniaturization, simple device architecture, and high sensitivity. However, the main challenges for in vivo electrochemical neurotransmitter sensors are limited target selectivity, large background signal and noise, and device fouling and degradation over time. Therefore, achieving simultaneous detection of multiple neurotransmitters in real time with long-term stability remains the focus of research. The purpose of this review paper is to summarize the recently developed sensing techniques with the focus on neurotransmitters as the target analyte, and to discuss the outlook of simultaneous detection of multiple neurotransmitter species. This paper is organized as follows: firstly, the common materials used for developing neurotransmitter sensors are discussed. Secondly, several sensor surface modification approaches to enhance sensing performance are reviewed. Finally, we discuss recent developments in the simultaneous detection capability of multiple neurotransmitters.

show abstract

Advanced materials for optical sensing and biosensing of neurotransmitters

Cited by 36 publications

References 128 publications

Photoelectroanalytical Sensor Based on TiO₂ Nanoparticles/Copper Tetrasulfonated Phthalocyanine for Detection of Dopamine Exploiting Light Emitting Diode Irradiation

Photoelectroanalytical Sensor Based on TiO₂ Nanoparticles/Copper Tetrasulfonated Phthalocyanine for Detection of Dopamine Exploiting Light Emitting Diode Irradiation

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Recent Advances in the Detection of Neurotransmitters

Contact Info

Product

Resources

About

Advanced materials for optical sensing and biosensing of neurotransmitters

Cited by 36 publications

References 128 publications

Photoelectroanalytical Sensor Based on TiO2 Nanoparticles/Copper Tetrasulfonated Phthalocyanine for Detection of Dopamine Exploiting Light Emitting Diode Irradiation

Photoelectroanalytical Sensor Based on TiO2 Nanoparticles/Copper Tetrasulfonated Phthalocyanine for Detection of Dopamine Exploiting Light Emitting Diode Irradiation

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Recent Advances in the Detection of Neurotransmitters

Contact Info

Product

Resources

About

Photoelectroanalytical Sensor Based on TiO₂ Nanoparticles/Copper Tetrasulfonated Phthalocyanine for Detection of Dopamine Exploiting Light Emitting Diode Irradiation

Photoelectroanalytical Sensor Based on TiO₂ Nanoparticles/Copper Tetrasulfonated Phthalocyanine for Detection of Dopamine Exploiting Light Emitting Diode Irradiation