Advanced Tumor Stage Is an Independent Risk Factor of Postoperative Infectious Complications After Colorectal Surgery

Abstract

Advanced tumors increase the risk of infectious complications after colorectal resection, with other risk factors including malnutrition, obesity, and resection by laparotomy. Optimization of modifiable risk factors through nutritional repletion and the choice of a minimally invasive operation should be considered.

Laparoscopic Versus Open Surgery for Gastric Gastrointestinal Stromal Tumors

“…The reduced invasiveness of the laparoscopic technique with less muscular trauma, less postoperative pain, less bowel manipulation, reduced inflammatory response and immunosuppression, and earlier postoperative activities may be considered to be the main reasons for explaining such results. 20 The conversion rate from laparoscopy to laparotomy was 14.2% higher than in most reported series [7% (range 0-25)] and probably reflects the multicentric character of our study including preliminary experiences. 13 Those converted patients were included in the laparoscopic group in an intent-to-treat analysis, reinforcing the beneficial effect of laparoscopy that we observed.…”

Sarcopenia, as defined by low muscle mass, strength and physical performance, predicts complications after surgery for colorectal cancer

“…Therefore, when age and sarcopenia were both included in the multivariate analysis, age was excluded as a confounding factor and sarcopenia became an independent risk factor. Several factors that were previously reported to be independent risk factors for complications after colorectal surgery, such as male gender [28] or advanced tumour stage [29], were not associated with postoperative complications in the present study. This may be due to the different patient characteristics and the different treatments.…”

Risk of Surgical Site Infection (SSI) following Colorectal Resection Is Higher in Patients With Disseminated Cancer: An NCCN Member Cohort Study

“…The frequency of superficial SSIs was similar in both groups. 16 Segal et al 17 found a similar association of disseminated cancer with organ space SSIs (adjusted odds ratio [AOR], 1.21; 95% CI, 1.02–1.44). 17 …”