Advances and challenges in umbilical cord blood and tissue bioprocessing: procurement and storage

Parker, Lindsey; Mansfield, Shaun; Sneddon, Kate; Charles, Ben; Rafiq, Qasim A.

doi:10.18609/cgti.2017.042

Cell Gene Therapy Insights 2017

DOI: 10.18609/cgti.2017.042

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Advances and challenges in umbilical cord blood and tissue bioprocessing: procurement and storage

Lindsey Parker¹,

Shaun Mansfield²,

Kate Sneddon³

et al.

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2024

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Advancements in Umbilical Cord Biobanking: A Comprehensive Review of Current Trends and Future Prospects

AlOraibi,

Taurin,

Alshammary

2024

SCCAA

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Biobanking has emerged as a transformative concept in advancing the medical field, particularly with the exponential growth of umbilical cord (UC) biobanking in recent decades. UC blood and tissue provide a rich source of primitive hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs) for clinical transplantation, offering distinct advantages over alternative adult stem cell sources. However, to fully realize the therapeutic potential of UC-derived stem cells and establish a comprehensive global UC-biobanking network, it is imperative to optimize and standardize UC processing, cryopreservation methods, quality control protocols, and regulatory frameworks, alongside developing effective consent provisions. This review aims to comprehensively explore recent advancements in UC biobanking, focusing on the establishment of rigorous safety and quality control procedures, the standardization of biobanking operations, and the optimization and automation of UC processing and cryopreservation techniques. Additionally, the review examines the expanded clinical applications of UC stem cells, addresses the challenges associated with umbilical cord biobanking and UC-derived stem cell therapies, and discusses the promising role of artificial intelligence (AI) in enhancing various operational aspects of biobanking, streamlining data processing, and improving data analysis accuracy while ensuring compliance with safety and quality standards. By addressing these critical areas, this review seeks to provide insights into the future direction of UC biobanking and its potential to significantly impact regenerative medicine.

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Advancements in Umbilical Cord Biobanking: A Comprehensive Review of Current Trends and Future Prospects

AlOraibi,

Taurin,

Alshammary

2024

SCCAA

View full text Add to dashboard Cite

show abstract

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Advances and challenges in umbilical cord blood and tissue bioprocessing: procurement and storage

Cited by 1 publication

References 56 publications

Advancements in Umbilical Cord Biobanking: A Comprehensive Review of Current Trends and Future Prospects

Advancements in Umbilical Cord Biobanking: A Comprehensive Review of Current Trends and Future Prospects

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