Advances in anti-tumor research based on bionic micro-nano technology

Gao, Jingpi; Yang, Ping; Li, Heying; Nan, Lijun; Liu, Xiaoran; Cai, Kaiyong; Li, Jinghua

doi:10.1016/j.jddst.2023.104674

Cited by 3 publications

(1 citation statement)

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“…Researchers and practitioners can fabricate devices that imitate or draw inspiration from biological systems to execute targeted functions, frequently surpassing the efficiency and efficacy of conventional devices. Medicine and healthcare are highly significant domains for applying micro/nanodevices [ 43 , 44 ]. Environmental monitoring is a field that extensively utilizes micro/nanodevices [ 45 ].…”

Section: Introductionmentioning

confidence: 99%

Bio-Inspired Nanomaterials for Micro/Nanodevices: A New Era in Biomedical Applications

Harun-Ur-Rashid,

Jahan,

Foyez

et al. 2023

Micromachines

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Exploring bio-inspired nanomaterials (BINMs) and incorporating them into micro/nanodevices represent a significant development in biomedical applications. Nanomaterials, engineered to imitate biological structures and processes, exhibit distinctive attributes such as exceptional biocompatibility, multifunctionality, and unparalleled versatility. The utilization of BINMs demonstrates significant potential in diverse domains of biomedical micro/nanodevices, encompassing biosensors, targeted drug delivery systems, and advanced tissue engineering constructs. This article thoroughly examines the development and distinctive attributes of various BINMs, including those originating from proteins, DNA, and biomimetic polymers. Significant attention is directed toward incorporating these entities into micro/nanodevices and the subsequent biomedical ramifications that arise. This review explores biomimicry’s structure–function correlations. Synthesis mosaics include bioprocesses, biomolecules, and natural structures. These nanomaterials’ interfaces use biomimetic functionalization and geometric adaptations, transforming drug delivery, nanobiosensing, bio-inspired organ-on-chip systems, cancer-on-chip models, wound healing dressing mats, and antimicrobial surfaces. It provides an in-depth analysis of the existing challenges and proposes prospective strategies to improve the efficiency, performance, and reliability of these devices. Furthermore, this study offers a forward-thinking viewpoint highlighting potential avenues for future exploration and advancement. The objective is to effectively utilize and maximize the application of BINMs in the progression of biomedical micro/nanodevices, thereby propelling this rapidly developing field toward its promising future.

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Section: Introductionmentioning

confidence: 99%

Bio-Inspired Nanomaterials for Micro/Nanodevices: A New Era in Biomedical Applications

Harun-Ur-Rashid,

Jahan,

Foyez

et al. 2023

Micromachines

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Atomic Engineering of Single‐Atom Nanozymes for Biomedical Applications

Shen,

Chen,

Qian

et al. 2024

Advanced Materials

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Single‐atom nanozymes (SAzymes) showcase not only uniformly dispersed active sites but also meticulously engineered coordination structures. These intricate architectures bestow upon them an exceptional catalytic prowess, thereby captivating numerous minds and heralding a new era of possibilities in the biomedical landscape. Tuning the microstructure of SAzymes on the atomic scale is a key factor in designing targeted SAzymes with desirable functions. In this review, we firstly discuss and summarize three strategies for designing SAzymes and their impact on reactivity in biocatalysis. The effects of choices of carrier, different synthesis method, coordination modulation of first/second shell, and the type and number of metal active centers on the enzyme‐like catalytic activity are unraveled. Next, we make a first attempt to summarize the biological applications of SAzymes in tumor therapy, biosensing, antimicrobial, anti‐inflammatory and other biological applications from different mechanisms. Finally, how SAzymes are designed and regulated for further realization of diverse biological applications is reviewed and prospected. We envisage that the comprehensive review presented within this exegesis will furnish novel perspectives and profound revelations regarding the biomedical applications of SAzymes.This article is protected by copyright. All rights reserved

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