Advances in Carotenoid Based Delivery Systems for Alleviating Inflammatory Bowel Disease

Zhang, Yan; Song, Jiangfeng; Wang, Hongjuan; Li, Ying; Wu, Caie

doi:10.1080/87559129.2023.2273928

Food Reviews International

2023

DOI: 10.1080/87559129.2023.2273928

|View full text |Cite

Advances in Carotenoid Based Delivery Systems for Alleviating Inflammatory Bowel Disease

Yan Zhang,

Jiangfeng Song,

Hongjuan Wang

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 95 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Oral Lactoferrin‐Responsive Formulation Anchoring around Inflammatory Bowel Region for IBD Therapy

Yang,

Shang,

et al. 2024

Adv Healthcare Materials

View full text Add to dashboard Cite

Oral formulation is the ideal treatment method for inflammatory bowel disease (IBD) therapy, but the mucosal damage and diarrhea symptoms impede the drug retention around the inflammatory region, severely limiting IBD therapeutic efficacy. To address this, an oral astaxanthin (Ast) precise delivery formulation is developed with the selective Ast anchoring around the inflammatory region by the novel lactoferrin (LF)‐responsive flocculation. This formulation also heightens the apparent solubility of Ast with the minimized edible safety risks for the edible raw materials. For in vivo IBD therapy, the precise delivery formulation exhibits remarkable outcomes, including a significant increase in colon length and a 100% survival rate. Furthermore, it is verified that the mechanism of treatment is primarily attributed to the improved immunoregulation, epithelial repair, and gut microbiota remodeling after the LF‐responsive flocculation. This effective inflammatory‐responsive delivery design is instructive and valuable to develop more precise delivery systems for IBD therapy.

show abstract

Oral Lactoferrin‐Responsive Formulation Anchoring around Inflammatory Bowel Region for IBD Therapy

Yang,

Shang,

et al. 2024

Adv Healthcare Materials

View full text Add to dashboard Cite

show abstract

Thermo-induced changes in the structure of lentil protein isolate (Lens culinaris) to stabilize high internal phase emulsions

Galvão,

Freitas,

Karatay

et al. 2023

International Journal of Biological Macromolecules

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Advances in Carotenoid Based Delivery Systems for Alleviating Inflammatory Bowel Disease

Cited by 2 publications

References 95 publications

Oral Lactoferrin‐Responsive Formulation Anchoring around Inflammatory Bowel Region for IBD Therapy

Oral Lactoferrin‐Responsive Formulation Anchoring around Inflammatory Bowel Region for IBD Therapy

Thermo-induced changes in the structure of lentil protein isolate (Lens culinaris) to stabilize high internal phase emulsions

Contact Info

Product

Resources

About