Advances in Exercise, Fitness, and Performance Genomics in 2010

Hagbèrg, James M.; Rankinen, Tuomo; Loos, Ruth J.F.; Pérusse, Louis; Roth, Stephen M.; Wolfarth, Bernd; Bouchard, Claude

doi:10.1249/mss.0b013e3182155d21

Cited by 72 publications

(92 citation statements)

References 62 publications

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“…However the study supported the decade long hypothesis for encouraging the ectmorphic mesomorph body type for the of Track and Field athletes with higher reciprocal Ponderal index [38]. Other studies also showed that mesomorphic component was a dominant characteristic of somatotype for Track and Field athletes compare to other two components [4,5,6,7,8,37,38].…”

Section: Discussionsupporting

confidence: 70%

“…Requirement of specific physique for good performance in sports had been supported by different studies [1]. Various studies had been attempted to relate performance level with body type and body composition [2,3,4,5,6]. Relationship between the leg length and performance level during running had been established by different studies [5,6,7,8].…”

Section: Introductionmentioning

confidence: 99%

“…Various studies had been attempted to relate performance level with body type and body composition [2,3,4,5,6]. Relationship between the leg length and performance level during running had been established by different studies [5,6,7,8]. Similarly, physiological aspects in terms of VO 2max had an important role in athletic performance which was revealed by different studies [9][10][11][12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

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Importance of Anthropometric Characteristics in Athletic Performance from the Perspective of Bangladeshi National Level Athletes' Performance and Body Type

Adhikari¹,

Pervin²,

Islam³

et al. 2014

AJSSM

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The significant role of anthropometric characteristics in sport performance besides other factors is well known. Requirement of specific physique for good performance in specific sports has been established in different studies. The athletic performance of Bangladesh is not that much well and that might be due to different physiological or psychological or skill level aspects. A physical and physiological study was conducted to find out the reason for poor performance of the Track and Field athletes as athletic performance was more dependent on physiological demands besides skill and techniques. Body composition, somatotype and VO 2max of twenty-eight national level athletes (15 male and 13 female) were studied at Bangladesh Institute of Sports (BKSP). Average height and weight of the female athletes of the present study were 157.6 cm (± 5.4) and 50.6 kg (± 4.5) respectively with an average age of 17.8 yr (± 1.6). The stature ranged between 149.0 cm and 166.2 cm whereas that of body weight was between 44.0 kg and 60.3 kg. Similarly their male counterparts possessed an average height of 171.2 cm (SD ± 7.5, range 157.4.cm -181.4 cm) with an average body mass of 62.7 kg (SD ± 8.2, range 47.2 kg-73.5 kg). A slightly high body fat% of 18.4 (SD ± 2.3, range 14.1% -22.0%) was observed for the female athletes whereas that of their male counterparts was 7.9% (SD ± 1.5, range 5.7% -11.3%). Average balanced mesomorph with less mesomorph component was observed for the female athletes (2.7±0.5−3.4±0.9−2.7±0.9) while that of their male counterparts was ectomorphic mesomorph with less mesomorph component (1.5±0.4−4.0±1.1−3.0±1.1). Normal range of body fat% was observed both in male and female athletes with slightly higher in females. An average VO 2max of 45.3 ml.kg -1.min -1 (SD ± 6.6, range 34.1-56.1) was observed for female athletes whereas that of their male counterparts was 59.1 ml.kg -1.min -1 (SD ± 5.3,. Anthropometric characteristics in terms of Somatotype of the Bangladeshi athletes were poor compare to Olympians and other international athletes though the physiological aspects in terms of VO 2max were more considerable compare to international athletes. Hence, poor performance of Bangladeshi athletics might be due to poor anthropometric characteristics which support the importance of Anthropometric characteristics in athletic performances.

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Section: Discussionsupporting

confidence: 70%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Importance of Anthropometric Characteristics in Athletic Performance from the Perspective of Bangladeshi National Level Athletes' Performance and Body Type

Adhikari¹,

Pervin²,

Islam³

et al. 2014

AJSSM

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“…Most of these studies (e.g., (4,11,31,33) were based on a case-control design and were characterized by the same limitations that we highlighted last year (19), and which were further addressed in a recent publication (8). Although some studies had replication data, the small sample size and the lack of clearly defined physiological phenotypes were consistent limiting factors (21,32).…”

Section: Endurance Performancementioning

confidence: 99%

Advances in Exercise, Fitness, and Performance Genomics in 2015

Sarzynski

Loos

Lucía

et al. 2016

Medicine &Amp; Science in Sports &Amp; Exercise

Self Cite

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This review of the exercise genomics literature emphasizes the highest quality papers published in 2011. Given this emphasis on the best publications, only a small number of published papers are reviewed. One study found that physical activity levels were significantly lower in patients with mitochondrial DNA mutations compared to controls. A two-stage fine mapping follow-up of a previous linkage peak found strong associations between sequence variation in the activin A receptor, type-1B (ACVR1B) gene and knee extensor strength, with rs2854464 emerging as the most promising candidate polymorphism. The association of higher muscular strength with the rs2854464 A-allele was confirmed in two separate cohorts. A study using a combination of transcriptomic and genomic data identified a comprehensive map of the transcriptomic features important for aerobic exercise training-induced improvements in maximal oxygen consumption, but no genetic variants derived from candidate transcripts were associated with trainability. A large-scale de novo meta-analysis confirmed that the effect of sequence variation in the fat mass and obesity-associated (FTO) gene on the risk of obesity differs between sedentary and physically active adults. Evidence for gene-physical activity interactions on type 2 diabetes risk was found in two separate studies. A large study of women found that physical activity modified the effect of polymorphisms in the lipoprotein lipase (LPL), hepatic lipase (LIPC), and cholesteryl ester transfer protein (CETP) genes, identified in previous genome-wide association study (GWAS) reports, on HDL-C. We conclude that a strong exercise genomics corpus of evidence would not only translate into powerful genomic predictors but would also have a major impact on exercise biology and exercise behavior research.

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“…This investigation is a subset of the FAMuSS study which is the largest study that has investigated candidate genes associated with muscle performance, and the first study to specifically investigate NOS3 variant associations with PA and muscle strength in humans [15]. Furthermore, FAMuSS 6 ISRN Vascular Medicine meets the criteria outlined by Hagberg et al [14,47] that are necessary for conducting exercise genomics studies including a large sample size, a well-structured exercise intervention with stringent assessment of phenotypes, and quality control of genotyping.…”

Section: Nos3 +894 G>tmentioning

confidence: 99%

Endothelial Nitric Oxide Synthase (NOS3) +894 G>T Associates with Physical Activity and Muscle Performance among Young Adults

Guidry

Kostek

Angelopoulos

et al. 2012

ISRN Vascular Medicine

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Objective. We examined the influence of missense polymorphism, endothelial nitric oxide synthase (NOS3) +894 G>T (rs1799983), on habitual physical activity (PA) and the muscle strength response to resistance training (RT). Methods. Men (n = 354) and women (n = 424; 24.3 ± 8.0 yr) were genotyped. Subjects reported hr/wk in vigorous and light intensity PA and sitting on the Paffenbarger PA questionnaire. One repetition maximum assessed muscle strength. Multivariable and repeated measures ANCOVA tested differences among NOS3 +894 G>T and PA and RT phenotypes by gender. Results. hr/wk in vigorous intensity PA (5.4 ± 1.2 versus 8.3 ± 0.4; P = 0.019), more hr/wk in light intensity PA (42.1 ± 2.4 versus 35.8 ± 0.7; P = 0.011), and less hr/wk sitting (37.6 ± 2.8 versus 45.8 ± 0.9; P = 0.006) than those with the G allele. Women with NOS3 +894 TT gained more absolute (4.4 ± 0.3 versus 3.7 ± 0.8 kg; P = 0.013) and relative (78.3 ± 5.8 versus 61.9 ± 1.8%; P = 0.007) strength than those with the G allele. Conclusions. NOS3 +894 G>T associated with PA among men and women and the muscle strength response to RT among women only. Our findings indicate the need for prospective studies examining the influence of NOS3 variants on PA and the muscle response to RT as well as elucidating underlying mechanistic pathways for the associations observed.

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Advances in Exercise, Fitness, and Performance Genomics in 2010

Cited by 72 publications

References 62 publications

Importance of Anthropometric Characteristics in Athletic Performance from the Perspective of Bangladeshi National Level Athletes' Performance and Body Type

Importance of Anthropometric Characteristics in Athletic Performance from the Perspective of Bangladeshi National Level Athletes' Performance and Body Type

Advances in Exercise, Fitness, and Performance Genomics in 2015

Endothelial Nitric Oxide Synthase (NOS3) +894 G>T Associates with Physical Activity and Muscle Performance among Young Adults

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