2024
DOI: 10.1007/s40820-024-01477-3
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Advances in Polysaccharide-Based Microneedle Systems for the Treatment of Ocular Diseases

Qingdong Bao,
Xiaoting Zhang,
Zhankun Hao
et al.

Abstract: The eye, a complex organ isolated from the systemic circulation, presents significant drug delivery challenges owing to its protective mechanisms, such as the blood-retinal barrier and corneal impermeability. Conventional drug administration methods often fail to sustain therapeutic levels and may compromise patient safety and compliance. Polysaccharide-based microneedles (PSMNs) have emerged as a transformative solution for ophthalmic drug delivery. However, a comprehensive review of PSMNs in ophthalmology ha… Show more

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