Advancing Computer-Aided Drug Discovery (ACADD): In-Silico Approach towards Nuclear Receptors by Big Data

Palaniammal, K.; Mani, M. Saravana Roentgen; Kumar, Rupesh

doi:10.9734/jpri/2021/v33i30a31612

Cited by 1 publication

(1 citation statement)

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“…UCSF Chimera is a program for the interactive visualisation and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available in both free (non-commercial) and commercial forms [7,9].…”

Section: Chimeramentioning

confidence: 99%

Review of bioinformatic tools used in Computer Aided Drug Design (CADD)

N¹,

Velmurugan²

2022

World J. Adv. Res. Rev.

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Drug discovery is а time consuming рrосess of finding out a new drug molecule. The process takes many years to complete and needs human resource. These is difficulties have been overcome by introducing computer programmes in drug discovery (CADD) which includes target identification, hit identification, and molecular modification of а lead compound to optimize desired effects and minimize side effects, based on the knowledge of their biological targets. Molecular modelling is the process of designing a molecule with a computer-based collection of programmes (in-silico design) for deriving, representing, and manipulating the structures and reactions of molecules. Numerous Software tools, online data bases and computer programmes are used in the field of CADD in which some relevant, user friendly and precise ones are reviewed in this article. Software is available for personal use and for commercial purposes. All these tools are highly useful in the field of drug design and discovery. The article will be helpful for selecting a tool for computer aided drug design.

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Section: Chimeramentioning

confidence: 99%