2024
DOI: 10.3748/wjg.v30.i40.4339
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Advancing diabetes management: Exploring pancreatic beta-cell restoration’s potential and challenges

Mona Mohamed Ibrahim Abdalla

Abstract: Diabetes mellitus, characterized by chronic hyperglycemia due to insulin deficiency or resistance, poses a significant global health burden. Central to its pathogenesis is the dysfunction or loss of pancreatic beta cells, which are res-ponsible for insulin production. Recent advances in beta-cell regeneration research offer promising strategies for diabetes treatment, aiming to restore endogenous insulin production and achieve glycemic control. This review explores the physiological basis of beta-cell function… Show more

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