2024
DOI: 10.1021/acs.iecr.4c00318
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Advancing Nitrobenzene Hydrogenation Process Understanding: A Multiscale Modeling Approach using Industrial Pharmaceutical Production Data

Wout Callewaert,
Bernardo V. Pessanha,
Jeroen Lauwaert
et al.

Abstract: The pharmaceutical industry is under increasing pressure to reduce production costs and operate within agile supply chains by leveraging the capabilities that come with integrated data infrastructures and increasing access to various forms of modeling. In contrast to bulk chemical production, pharmaceutical productions typically operate at significantly lower volumes and allow for narrower variability in critical parameters due to tightly defined operating ranges. This makes the data acquired from the process … Show more

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