Aedes Triseriatus and La Crosse Virus: Geographic Variation in Vector Susceptibility and Ability to Transmit *

Mode of transmission and the evolution of arbovirus virulence in mosquito vectors

“…albopictus infected with San Angelo virus, another member of the California serogroup ( Tesh 1980). Nevertheless, although these effects negatively impact the fitness of mosquitoes and may, therefore, act as a selective pressure on vector populations (Grimstad et al 1977), the cost to the virus may be relatively small. Examination of the various mechanisms of arbovirus virulence in vectors (see below) can help explain why.…”

Variation in Susceptibility Among Clony Strains of Culex Tritaeniorhynchus to Japanese Encephalitis Virus Infection

“…Studies on vector competence have been done with C. tarsalis for Western equine encephalomyelitis virus (Hardy et al, 1976(Hardy et al, , 1978, with Aedes albopictus and A. aegy p ti for dengue viruses Gubler et al, 1979), with A. albopictus for chikungunya virus (Tesh et al ., 1976), with A. triseriatus for La Crosse virus (Grimstad et al, 1977), with A. aegypti for yellow fever virus (Aitken et al, 1977), and with Southern Asia and the Far East strains of C. tritaeniorhynchus for West Nile virus (Ashmed et al, 1979).…”

The role of Culex pipiens mosquitoes in transmission of West Nile virus in Europe

“…Our study shows that such variation can be partly explained by temperature, but other complex interactions between viral strains, viral titers, and geographically distinct vector populations have been shown to play a role as well (Anderson et al 2010, Fros et al 2015a, Zouache et al 2014). In addition, colonization in the laboratory could have influenced the outcomes of these vector competence studies (Gargan et al 1983, Grimstad et al 1977, Jones & Foster 1978, Lorenz et al 1984). Such effects have been shown to occur after 8 generations for Cx.…”

“…Such effects have been shown to occur after 8 generations for Cx. pipiens mosquitoes infected with Rift Valley Fever virus (Gargan et al 1983), but this is dependent on the number of females the colony was established with, and selection pressures in the rearing environment (Grimstad et al 1977, Jones & Foster 1978. In order to fully understand factors that are required for WNV transmission, a direct comparison should be made between vector competence of recently established mosquito populations originating from endemic and non-endemic areas at different temperatures (chapter 5 of this thesis).…”

“…Vector competence studies have been conducted with mosquitoes collected in the field, or mosquitoes that were reared for many generations in the laboratory. Laboratory colonization can affect vector competence of mosquitoes for viruses (Gargan et al 1983, Grimstad et al 1977. Thus, use of field-derived mosquitoes is necessary to reliably estimate vector competence of mosquito populations in the field.…”