Age‐ and Serotype‐Specific Pediatric Invasive Pneumococcal Disease: Insights from Systematic Surveillance in Santiago, Chile, 1994–2007

Lagos, Rosanna; Muñoz, Alma; Martin, Oriana San; Maldonado, Aurora; Hormázabal, Juan Carlos; Blackwelder, William C.; Levine, Myron M.

doi:10.1086/593334

Cited by 70 publications

(75 citation statements)

References 33 publications

(42 reference statements)

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“…As in previous studies (21,22), most (94.6%) children hospitalized with acute respiratory disease were aged less than three years. Analysis of data from the prospective surveillance suggests that most (80.4%) suspected invasive pneumococcal diseases in Vietnamese children manifests initially as pneumonia.…”

Section: Characteristics Of Patientssupporting

confidence: 73%

Treatment Costs of Pneumonia, Meningitis, Sepsis, and Other Diseases among Hospitalized Children in Viet Nam

Anh

Riewpaiboon

Tho³

et al. 2010

J Health Popul Nutr

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The aim of this study was to estimate the costs of treatment of children who present with the signs and symptoms of invasive bacterial diseases in Khanh Hoa province, Viet Nam. The study was an incidencebased cost-of-illness analysis from the health system perspective. The hospital costs included labour, materials and capital costs, both direct and indirect. Costs were determined for 980 children, with an average age of 12.67 months (standard deviation±11.38), who were enrolled in a prospective surveillance at the Khanh Hoa General Hospital during [2005][2006]. Of them, 57% were male. By disease-category, 80% were suspected of having pneumonia, 8% meningitis, 3% very severe disease consistent with pneumococcal sepsis, and 9% other diseases. Treatment costs for suspected pneumonia, meningitis, very severe disease, and other diseases were US$ 31, US$ 57, US$ 73, and US$ 24 respectively. Costs ranged from US$ 24 to US$ 164 across different case-categories. Both type of disease and age of patient had statistically significant effects on treatment costs. The results showed that treatment costs for bacterial diseases in children were considerable and might differ by as much as seven times among invasive pneumococcal diseases. Changes in costs were sensitive to both age of patient and case-category. These cost-of-illness data will be an important component in the overall evidence base to guide the development of vaccine policy in Viet Nam.

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Section: Characteristics Of Patientssupporting

confidence: 73%

Treatment Costs of Pneumonia, Meningitis, Sepsis, and Other Diseases among Hospitalized Children in Viet Nam

Anh

Riewpaiboon

Tho³

et al. 2010

J Health Popul Nutr

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“…4,7 Serotype 14 is the major IPD pathogen among Chilean children aged 6-35 months but serotype 5 predominates among infants 0-5 months of age and serotype 1 is the most frequent in children aged 36-59 months and 5-14 years. 4 Moreover, serotypes 5 and 1 are more invasive than other serotypes.…”

Section: Introductionmentioning

confidence: 99%

Safety and immunogenicity of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) in Chilean children

Lagos¹,

Muñoz²,

Levine³

et al. 2011

Human Vaccines

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“…Lagos R. y cols., evaluaron la cobertura teórica otorgada por estas vacunas para Chile, en base a un estudio de vigilancia activa de ENI efectuado en la Región Metropolitana entre los años 2000 y 2007, en lactantes y niños hospitalizados con edad igual o menor a 59 meses. Estos autores comprobaron que 54,4% de los casos de ENI correspondían a serotipos cubiertos por la vacuna 7-valente, en tanto que 72,4% por la vacuna 10-valente y finalmente 82,5% por la 13-valente 7 .…”

Section: Discussionunclassified

Meningitis neumocóccica por serotipo 19 A, de curso fatal: ¿Un caso prevenible?

Rivacoba

Cofré

Santolaya

2016

Rev. chil. infectol.

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Age‐ and Serotype‐Specific Pediatric Invasive Pneumococcal Disease: Insights from Systematic Surveillance in Santiago, Chile, 1994–2007

Abstract: Clinical syndromes of IPD and predominant serotypes vary with age.

Cited by 70 publications

References 33 publications

Treatment Costs of Pneumonia, Meningitis, Sepsis, and Other Diseases among Hospitalized Children in Viet Nam

Treatment Costs of Pneumonia, Meningitis, Sepsis, and Other Diseases among Hospitalized Children in Viet Nam

Safety and immunogenicity of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) in Chilean children

Meningitis neumocóccica por serotipo 19 A, de curso fatal: ¿Un caso prevenible?

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