Age at menarche and risks of gestational diabetes mellitus: a meta-analysis of prospective studies

Xiao, Ya L.; Chen, Ruixue; Chen, Minghao; Luo, Anqi; Chen, Dayi; Liang, Qiuer; Cai, Yunfei; Chen, Liguo; Zhao, Xiaoshan

doi:10.18632/oncotarget.23658

Cited by 14 publications

(10 citation statements)

References 22 publications

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“…In Asia, the prevalence of GDM ranges from 0.7 to 51.0% [28–30]. This vast disparity in prevalence rates may be due to differences in ethnicity [28, 30], diagnostic criteria [31–33], screening strategies [29, 34], and population characteristics [35, 36].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and risk factors of gestational diabetes mellitus in Asia: a systematic review and meta-analysis

Lee

Ching

Ramachandran

et al. 2018

BMC Pregnancy Childbirth

382

273

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BackgroundGestational diabetes mellitus (GDM) is a of the major public health issues in Asia. The present study aimed to determine the prevalence of, and risk factors for GDM in Asia via a systematic review and meta-analysis.MethodsWe systematically searched PubMed, Ovid, Scopus and ScienceDirect for observational studies in Asia from inception to August 2017. We selected cross sectional studies reporting the prevalence and risk factors for GDM. A random effects model was used to estimate the pooled prevalence of GDM and odds ratio (OR) with 95% confidence interval (CI).ResultsEighty-four studies with STROBE score ≥ 14 were included in our analysis. The pooled prevalence of GDM in Asia was 11.5% (95% CI 10.9–12.1). There was considerable heterogeneity (I2 > 95%) in the prevalence of GDM in Asia, which is likely due to differences in diagnostic criteria, screening methods and study setting. Meta-analysis demonstrated that the risk factors of GDM include history of previous GDM (OR 8.42, 95% CI 5.35–13.23); macrosomia (OR 4.41, 95% CI 3.09–6.31); and congenital anomalies (OR 4.25, 95% CI 1.52–11.88). Other risk factors include a BMI ≥25 kg/m2 (OR 3.27, 95% CI 2.81–3.80); pregnancy-induced hypertension (OR 3.20, 95% CI 2.19–4.68); family history of diabetes (OR 2.77, 2.22–3.47); history of stillbirth (OR 2.39, 95% CI 1.68–3.40); polycystic ovary syndrome (OR 2.33, 95% CI1.72–3.17); history of abortion (OR 2.25, 95% CI 1.54–3.29); age ≥ 25 (OR 2.17, 95% CI 1.96–2.41); multiparity ≥2 (OR 1.37, 95% CI 1.24–1.52); and history of preterm delivery (OR 1.93, 95% CI 1.21–3.07).ConclusionWe found a high prevalence of GDM among the Asian population. Asian women with common risk factors especially among those with history of previous GDM, congenital anomalies or macrosomia should receive additional attention from physician as high-risk cases for GDM in pregnancy.Trial registrationPROSPERO (2017: CRD42017070104).

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Section: Introductionmentioning

confidence: 99%

Prevalence and risk factors of gestational diabetes mellitus in Asia: a systematic review and meta-analysis

Lee

Ching

Ramachandran

et al. 2018

BMC Pregnancy Childbirth

382

273

View full text Add to dashboard Cite

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“…The precise mechanism by which early age at menarche may increase the risk of GDM is not clear. Some studies indicated that the early age at menarche was a risk factor of GDM [12–14]. Additionally, Early age at menarche has been associated with risk factors for GDM such as excessive pre-pregnancy obesity [15–17], insulin resistance [18], and hormonal changes [19, 20].…”

Section: Introductionmentioning

confidence: 99%

Age at menarche and risk of gestational diabetes mellitus: a population-based study in Xiamen, China

Wang

Yan

Shi

et al. 2019

BMC Pregnancy Childbirth

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Background It has been reported that earlier age at menarche is associated with a higher risk for type 2 diabetes mellitus. However, the relationship between age at menarche and gestational diabetes mellitus is inconsistent across studies. We hypothesized that an earlier age at menarche would predict the gestational diabetes mellitus risk. Methods This was a population-based, retrospective cohort study of 70,041 women aged 18 to 53 years old, conducted between 2011 and 2018. The subjects were recruited from the Medical Birth Registry in Xiamen, China. Age at menarche was categorized as 8–12, 13, 14, 15, 16–19 years old. Logistic regression analysis and spline analysis was used to assess the risk of the menarche age group for gestational diabetes mellitus. Linear regression analysis was performed to evaluate independent associations between age at menarche and fasting plasma glucose and blood glucose 1 hour and 2 hours after a 75-g of glucose load between 24 and 28 weeks’ gestation. Results The overall prevalence of GDM was 17.6%. After adjustment for family history of diabetes, earlier age at menarche (8–12, and 13 years old) was associated with increased odds for GDM (OR, 1.08; 95% CI, 1.02–1.15, and OR, 1.07; 95% CI, 1.03–1.14, respectively) compared with average age at menarche (14 years old). With further adjustment for pre-pregnancy body mass index, blood pressure, educational level, age at delivery, and hepatitis B surface antigen status, this association was attenuated (OR, 0.93, and OR, 1.02, respectively). Multivariable-adjusted spline regression models showed a linear dose-response association between age at menarche and GDM (P for nonlinearity, 0.203; P for linearity, 0.006). On linear regression analysis, earlier age at menarche was significantly associated with increased blood glucose one and 2 hours after a glucose load but not with the fasting plasma glucose. Conclusions As expected, early age at menarche was found to be associated with an increased risk of gestational diabetes mellitus. However, this association may be mediated by potential confounding factors other than age. An additional finding was that earlier menarche was significantly related with elevated pregnancy glucose concentrations after a glucose load.

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“…Prevalence of GDM varies worldwide based on population characteristics (e.g. maternal age, socioeconomic status or body composition) (Huvinen et al, 2018;Xiao et al, 2018), race/ ethnicity (Alfadhli et al, 2015) and diagnostic criteria used for screening (Harper et al, 2016;Adam and Rheeder, 2017;Lauring et al, 2018;Nguyen et al, 2018). It has been reported that GDM affects between 1% and 28% of pregnant women worldwide (Jiwani et al, 2012).…”

Section: Prevalence Of Gestational Diabetes Mellitusmentioning

confidence: 99%

Gestational diabetes mellitus management: diet and lifestyle

Allehdan

Basha

Tayyem

2020

NFS

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Purpose Gestational diabetes mellitus (GDM) is one of the most common complications of pregnancy. GDM is defined as glucose intolerance of variable severity with onset or first recognition during pregnancy. The purpose of this paper is to produce information on prevalence, screening and diagnosis, pathophysiology and dietary, medical and lifestyle management of GDM. Design/methodology/approach This literature review aimed to document and record the results of the most updated studies published dealing with dietary, medical and lifestyle factors in managing GDM. Findings The prevalence of GDM differs worldwide based on population characteristics, race/ethnicity and diagnostic criteria. The pathophysiology of GDM is multifactorial and it is likely that genetic and environmental factors are associated with the occurrence of GDM. Medical nutritional therapy remains the mainstay of GDM management and aerobic and resistance physical activities are helpful adjunctive therapy when euglycemia is not attained by the medical nutritional therapy alone. When diet and exercise fail to achieve glycemic control, pharmacological agents such as insulin therapy and oral hypoglycemic medications are prescribed. Plasma glucose measurement is an essential part of glycemic control during pregnancy, as well as glycemic control can be evaluated using indicators of glycemic control such as hemoglobin A1c (HbA1c), glycated albumin and fructosamine. Originality/value This review is a comprehensive review that illustrates the effect of healthy diet, medical therapy and lifestyle change on improving GDM condition.

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Age at menarche and risks of gestational diabetes mellitus: a meta-analysis of prospective studies

Cited by 14 publications

References 22 publications

Prevalence and risk factors of gestational diabetes mellitus in Asia: a systematic review and meta-analysis

Prevalence and risk factors of gestational diabetes mellitus in Asia: a systematic review and meta-analysis

Age at menarche and risk of gestational diabetes mellitus: a population-based study in Xiamen, China

Gestational diabetes mellitus management: diet and lifestyle

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