Age-dependent changes in bone mineral density for males and females aged 10-80 years

Abstract

BACKGROUND: One of the most accurate and highly reproducible techniques is dual- energy x-ray absorptiometry (DXA). DXA device used to measure BMD, BMC, T-score, Z-score, and consequently used to measure fat mass (FM) and lean mass (LM) for different body sites such as arms, ribs, thoracic spine, lumbar spine, pelvis, legs and whole body. DXA technique is widely used in clinical application researches like diagnosing and treating osteoporosis in elderly men and women with different diseases and assessment of skeleton status. METHODS: One hundred and seventy-six males and females participated in the current study consisting of 48 males and 128 females were evaluated by Dual Energy X-ray Absorptiometry (DXA). RESULTS: The estimated correlation coefficients values were as follows: total BMD depending on segmental BMD of arms, legs were fitted with correlation coefficient of (r=0.92) and (r=0.91) respectively; also it were fitted with (r=0.85), (r=0.84), (r=0.73), (r=0.70), and (r=0.65) for head, pelvis, ribs, thoracic spine and lumber spine respectively; p<0.0001. CONCLUSION: The mean total bone mineral density BMD of the total body for both genders shows highly significant; (p-value = 0.0001) through the ages (20-29). The same results are shown in the ages of (60-69) years with a significant relationship between males and females; (p=0.01). All the other groups (10-19), (30-39), (40-49), (50-59) and (70-80) years showed no significant relationship between both genders, where all mean total BMD amounts were small in female subgroups; p>0.01.