As it is impossible to simulate the whole process of evacuation in case of emergencies, based on the analysis and comparison of existing evacuation simulation models, considering the intelligence, interaction and autonomy of agents, multi-agent technology is introduced to model the emergency evacuation model. In this model, the evacuation space is divided into equal squares. In the decisionmaking process of selecting the evacuation exit, the distance from the individual to the exit, the number of people in the field of vision, the number of obstacles and the relevant density are comprehensively considered. No guide, fixed instructions and guidance for the three cases of evacuation process simulation, in the simulation, considering the number of the position and exit, simulation results showed that increasing the exit quantity and the width , In the process of evacuation, guides are added to make real-time direction guidance for agents, which can greatly improve the efficiency of evacuation. The research has very important reference significance for formulating scientific and reasonable emergency evacuation plan and reducing various losses caused by disasters.