Aggregation-induced emission-based competitive lateral flow immunoassay for rapid detection of sulfamethazine in honey

Wang, Zexiang; Song, Huacan; Zhang, Ganggang; Liu, Jintao; Xia, Jun; Peng, Juan; Lai, Weihua

doi:10.1080/09540105.2019.1689929

Cited by 23 publications

(11 citation statements)

References 35 publications

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“…The detection methods for these micromolecules are always combined with an immunoassay to ensure their sensitive and specific analysis. [ 148 ] A specific veterinary medicine and its analogues have similar structures and properties, and these analogues may be used in animal husbandry. The antibody that recognizes a specific class of drugs is the best choice for multiple‐ residue detection LFA.…”

Section: Applicationsmentioning

confidence: 99%

An Overview for the Nanoparticles‐Based Quantitative Lateral Flow Assay

Wang

Zhao

et al. 2021

Small Methods

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The development of the lateral flow assay (LFA) has received much attention in both academia and industry because of their broad applications to food safety, environmental monitoring, clinical diagnosis, and so forth. The user friendliness, low cost, and easy operation are the most attractive advantages of the LFA. In recent years, quantitative detection has become another focus of LFA development. Here, the most recent studies of quantitative LFAs are reviewed. First, the principles and corresponding formats of quantitative LFAs are introduced. In the biomaterial and nanomaterial sections, the detection, capture, and signal amplification biomolecules and the optical, fluorescent, luminescent, and magnetic labels used in LFAs are described. The invention of dedicated strip readers has drawn further interest in exploiting the better performance of LFAs. Therefore, next, the development of dedicated reader devices is described and the usefulness and specifications of these devices for LFAs are discussed. Finally, the applications of LFAs in the detection of metal ions, biotoxins, pathogenic microorganisms, veterinary drugs, and pesticides in the fields of food safety and environmental health and the detection of nucleic acids, biomarkers, and viruses in clinical analyses are summarized.

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Section: Applicationsmentioning

confidence: 99%

An Overview for the Nanoparticles‐Based Quantitative Lateral Flow Assay

Wang

Zhao

et al. 2021

Small Methods

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“…The group then utilized the same AIEFM but with a different antibody, integrating with competitive LFIA to detect sulfamethazine and norfloxacin (Table ). − These results suggest that AIEFM has great potential to construct more sensitivity analysis platforms.…”

Section: Application Of Aiegens-based Immunoassaysmentioning

confidence: 93%

AIEgens: Next Generation Signaling Source for Immunoassays?

Dou

Wang

et al. 2022

ACS Sens.

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Luminogens with aggregation-induced emission (AIEgens) properties have numerous broad applications in fields of chemical and biological analyses due to their exceptional photostability, excellent signal reliability, high quantum yield, and large Stokes’ shift. In particular, AIEgens also bring new blood for immunoassay. Since publication of the first 2004 paper, AIEgens-based immunoassays have received significant attention because of their high sensitivity, specificity, accuracy, and reliability. However, until now, there have been no comprehensive literature reviews focused on the evolving field of AIEgens-based immunoassays. Thus, we have extensively reviewed AIEgens-based immunoassays from their basic working principles to specific applications. We focus on several fundamental elements of AIEgens-based immunoassays, including the typical structures of AIEgens, emission mechanism of AIEgens probes, function of AIEgens in immunoassays, and platform of AIEgens-based immunoassays. Then, the representative applications of AIEgens-based immunoassays in food safety, medical diagnostics, and environmental monitoring are explored. Thus, proposals on how to further improve the AIEgens-based immunoassay performance are also discussed, as well as future challenges and perspectives, aiming to provide brief and valid guidelines for choosing suitable AIEgens-based immunoassays according to specific application requirements.

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“…Due to strong π-π interactions in the aggregated state, a high concentration of traditional organic dyes may sometimes suffer from aggregation-induced quenching [ 40 ]. Therefore, materials based on aggregation-induced emission (AIE) became a new generation of fluorescent labels because of the superior brightness in the aggregate state, larger Stokes shift, and higher relative quantum yield [ 41 , 42 ]. Compared to individual fluorophores, these fluorescent microspheres drastically amplify detection signals, which are particularly attractive for detection in food samples to overcome the background fluorescence.…”

Section: Fluorescent Nanoparticlesmentioning

confidence: 99%

“… Schematic illustration of fluorescent lateral flow immunoassay for veterinary drug detection: (a) traditional assay (figure created based on ref. [ 41 ]); (b) combined with immunomagnetic separation (figure created based on ref. [ 71 ]); (c) multiplex lateral flow immunoassay (figure created based on ref.…”

Section: Figmentioning

confidence: 99%

Nanomaterial-based fluorescent biosensor for veterinary drug detection in foods

Tao¹,

Peng²,

Liu³

2020

Journal of Food and Drug Analysis

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Veterinary drugs have been widely used in the food industry. Their residues in food products need to be tightly regulated to ensure food safety. In particular, some veterinary drugs are still used illegally, although they have already been banned. Nanomaterials are playing an increasingly important role in analytical chemistry due to their unique properties. Compared to traditional organic dyes and colloidal gold nanoparticle labels, fluorescent nanomaterials appear particularly attractive for the detection of veterinary drug residues. This review summarizes recent advancements of fluorescent biosensors using nanomaterials for the detection of veterinary drug residues in foods. The useful properties of each type of fluorescent nanomaterial are first discussed such as large Stokes shifts, long emission lifetime, and high quantum yields, which are useful for detection in food-related sample matrix. The following target recognition molecules are then reviewed individually including antibodies, aptamers, molecularly imprinted polymers, and metal ion coordination based ligands. Representative bioconjugation and assay methods are discussed for each recognition mechanism. Finally, a few future research directions are outlined in the last section of this review.

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Aggregation-induced emission-based competitive lateral flow immunoassay for rapid detection of sulfamethazine in honey

Cited by 23 publications

References 35 publications

An Overview for the Nanoparticles‐Based Quantitative Lateral Flow Assay

An Overview for the Nanoparticles‐Based Quantitative Lateral Flow Assay

AIEgens: Next Generation Signaling Source for Immunoassays?

Nanomaterial-based fluorescent biosensor for veterinary drug detection in foods

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