Abstract:The study of immunity in non-model organisms has the potential to reveal the evolved diversity of the immune system. However, such studies are hampered by the paucity of species-specific reagents. Advances in single-molecule RNA-ISH overcomes these setbacks and allows for the detection of potentially dozens of gene targets in a single tissue section. We examined the spatial expression of immune genes in the splenic tissue of a teleost, threespine stickleback, using the advanced multiplexed RNAScope Hiplex assa… Show more
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