Aggressive angiomyxoma presenting with back and perineal bulge; a complex surgical approach: A case report

Faraj, Walid; Houjeij, Mohamad; Haydar, Ali; Nassar, Hussein; Nounou, Ghina El; Khalife, Mohamad

doi:10.1016/j.ijscr.2016.05.047

Cited by 8 publications

(7 citation statements)

References 6 publications

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“…Distant metastatic disease, however, is rare. There are only two cases described in the literature with pulmonary metastases and six mediastinal lymph nodes [7][8][9][10]. In the present case, no metastatic disease was detected in the extension study, but in the pathological study, involvement of the deeper surgical margin of the lesion was observed, although this condition does not seem to affect the risk of recurrence, which is high per se [11].…”

Section: Discussionmentioning

confidence: 42%

Genital Prolapse in Pregnant Woman as a Presentation of Aggressive Angiomyxoma: Case Report and Literature Review

et al. 2022

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Background: Aggressive angiomyxoma is a rare entity within mesenchymal cell neoplasms, especially in pregnant women. Its main characteristic is the ability to infiltrate neighboring structures and to recur. Case Presentation: We present the case of a pregnant woman who debuted with a genital prolapse in the second trimester of pregnancy. She was diagnosed with bilateral ovarian teratomas and a pelvic mass of which the diagnosis could not be established until delivery. The route of delivery used was cesarean section since the genital prolapse behaved as a previous tumor. After the puerperium, the patient was referred for consultation to complete the study of the mass. The extension study was carried out with a negative result. The patient underwent surgery for tumor exeresis. Hormonal treatment was not administered according to the patient’s preferences. Conclusions: Aggressive angiomyxoma is a benign neoplasm that should be considered in the differential diagnosis of pelvic tumors in women. In pregnant women, the vaginal route of delivery is not contraindicated as long as the tumor does not obstruct the birth canal. The definitive treatment is surgery, preferably performed in a second stage after delivery.

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Section: Discussionmentioning

confidence: 42%

Genital Prolapse in Pregnant Woman as a Presentation of Aggressive Angiomyxoma: Case Report and Literature Review

et al. 2022

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“…As emerged from our experience, and confirmed in the literature, the aspect of an aggressive angiomyxoma is often like a benign neoformation, such as lipomas or cysts, with a sort of soft, compact texture [ 2 , 4 , 5 , 6 ] and lobulated or spherical form, with an undefined capsule. The aggressivity of this type of tumor is usually limited to the nearest tissues, but some rare cases of pulmonary and lymph nodal metastasis have been reported [ 24 , 25 , 26 , 27 ].…”

Section: Discussionmentioning

confidence: 99%

“…The uniqueness of our work is not only for the analysis of the pathological management, but also for the presence of a complex, ongoing twin pregnancy and the observed sequelae of the treatment. To our knowledge, this is the most updated review on the topic [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 ]. The variety of the possible body locations, the association with pregnancy, and the few cases known in the literature make it difficult to formulate unique guidelines on this subject.…”

Section: Discussionmentioning

confidence: 99%

Aggressive Pelvic Angiomyxoma in a Patient with Twin Pregnancy: Diagnosis, Treatment, and Clinical Complications in Light of the Literature

Aquino

Tinelli²,

Libretti

et al. 2023

Medicina

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(1) Background: Aggressive angiomyxoma is a mesenchymal cancer that is rare during pregnancy. It is a neoplasm that relapses and infiltrates the nearest structures. Our aim is to evaluate the management and outcomes of an observed case, in light of the current literature. (2) Methods: We observed this condition at the “Maggiore della Carità” Hospital in Novara (Italy) in a patient with an initial twin pregnancy and a suspected pelvic mass. The words “angiomyxoma” and “pregnancy” were searched on the main online scientific search sources (PubMed, Google Scholar, Scopus, WES, and Embase, etc.). (3) Results: The patient underwent surgery with a complicated follow-up, but recent negative controls. We analyzed the literature about the topic and found only 24 similar clinical cases. (4) Conclusions: Considering the current literature, it is useful to assess an aggressive angiomyxoma in the differential diagnosis of soft masses in pregnant women. The treatment of choice is surgical excision, and vaginal delivery is feasible. The therapeutic decision depends on each case.

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“…[ 9 ] The longest recurrence time reported in the literature is 20 years. [ 16 ] There are even reports of lung metastasis [ 17 , 18 ] and death [ 19 ] in patients. Therefore, patients need long-term follow-up after operation.…”

Section: Discussionmentioning

confidence: 99%

Aggressive angiomyxoma of pelvis: A case report and literature review

Lin

Wang

2022

Medicine

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Rationale: Aggressive angiomyxoma (AAM) is a rare mesenchymal tumor primarily involving the lower genital tract of reproductive females. It often shares pathologic morphology with other mesenchymal lesions, which result in diagnostic difficulties for pathologists.Patient concerns and diagnoses: We described the case of a 32-year-old female presenting with a pelvic mass. Imaging examination showed a "swirling sign" within the mass. The mass was 10.2 × 10 × 7.7 cm, located in the right front of the uterus, with unclear demarcation from the surrounding organs and tissues. The gross appearance was grayish brown with a solid section and a myxedematous cut surface. Microscopically, it was a mesenchymal tumor with a presence of perivascular smooth muscle fibers radiating from the blood vessel and an infiltrative growth pattern. The pelvic AAM was diagnosed based on clinicopathologic and imaging features.Interventions and outcomes: A surgery with local excision of the mass was performed. The patient experienced 1 relapse during 2-year follow-up and underwent the radiation therapy.Lessons: When the pathological morphology of AAM overlaps with other mesenchymal lesions, the comprehensive understanding of tumor clinicopathological characteristics combined with imaging features is important for the accurate diagnosis of AAM.

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Aggressive angiomyxoma presenting with back and perineal bulge; a complex surgical approach: A case report

Abstract: Highlights90% of patients are women.Different incisions allows full mobilization of the tumor.Wide excision should keep capsule intact.R0 resection should be achieved.Follow-up should be at 1–2 yearly intervals.

Cited by 8 publications

References 6 publications

Genital Prolapse in Pregnant Woman as a Presentation of Aggressive Angiomyxoma: Case Report and Literature Review

Genital Prolapse in Pregnant Woman as a Presentation of Aggressive Angiomyxoma: Case Report and Literature Review

Aggressive Pelvic Angiomyxoma in a Patient with Twin Pregnancy: Diagnosis, Treatment, and Clinical Complications in Light of the Literature

Aggressive angiomyxoma of pelvis: A case report and literature review

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