Aggressive primary thyroid lymphoma invading the internal jugular vein: a case series

Su, Xuejiao; Han, Xue; Ma, Buyun

doi:10.21037/qims-22-649

Cited by 1 publication

(2 citation statements)

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“…The early transformation of HT into PTL is difficult to assess, and sometimes relies on the careful and subtle detection of a hypoechoic mass of convex contours within the underlying hypoechoic LT tissue. Unclear boundaries internal jugular vein invasion/thrombosis and lymphadenopathies are less frequent than in ATC [ 26 , 27 ]. Identifying echogenic fibrous strands [ Figure 1 B] that are typical features in favour of PTL could be the key- point for differentiating PTL from ATC.…”

Section: Discussionmentioning

confidence: 99%

“…Homogeneous vascularized mass without calcification and cystic necrosis but with posterior acoustic enhancement are typical features of PTL compared to ATC [ 12 , 25 , 29 ] and MTT [ 13 , 14 , 17 , 18 , 19 , 20 ]. The invasion of the internal jugular vein (IJV) occurs exceptionally in PTL [ 26 ] and MTT [ 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 ], and is quite common in ATC (33%) [ 28 ]. Vasculature was reported to be increased in PTL [ Figure 1 ] when compared to ATC.…”

Section: Discussionmentioning

confidence: 99%

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Fast Track Management of Primary Thyroid Lymphoma in the Very Elderly Patient

Marcy¹,

Bauduer

Thariat

et al. 2023

Current Oncology

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A rapid growing cervical mass mobile while swallowing is the most common clinical presentation of severe thyroid malignancy. A 91-year-old female patient with a history of Hashimoto thyroiditis presented with clinical compressive neck symptoms. The patient had gastric Maltoma diagnosed that was surgically resected thirty years ago. A straightforward process was needed to reach full histological diagnosis and initiate prompt therapy. Ultrasound (US) showed a 67 mm hypoechoic left thyroid mass with reticulated pattern without signs of locoregional invasion. Percutaneous trans isthmic US-guided 18G core needle biopsy (CNB) disclosed diffuse large B cell lymphoma of the thyroid gland. FDG PET revealed two distinct thyroid and gastric foci (both SUVmax 39.1). Therapy was initiated rapidly to decrease clinical symptoms in this aggressive stage III primitive malignant thyroid lymphoma. The prognostic nomogram was calculated by using a seven-item scale, which disclosed a one-year overall survival rate of 52%. The patient underwent three R-CVP chemotherapy courses, then refused further treatment and died within five months. Real-time US-guided CNB approach led to rapid patient’s management that was tailored to patient’s characteristics. Transformation of Maltoma into diffuse large B cell lymphoma (DLBCL) into two body areas is deemed to be extremely rare.

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Section: Discussionmentioning

confidence: 99%