AGL61 Interacts with AGL80 and Is Required for Central Cell Development in Arabidopsis

Steffen, Joshua G.; Kang, Il-Ho; Portereiko, Michael F.; Lloyd, A. C.; Drews, Gary N.

doi:10.1104/pp.108.119404

Cited by 132 publications

(130 citation statements)

References 42 publications

Supporting

Mentioning

125

Contrasting

Unclassified

Order By: Relevance

“…Relatively few genes have been shown to be required for both central cell identity and fusion of polar nuclei, e.g. the transcription factors DIANA/AGAMOUS LIKE 61 (DIA/AGL61) and AGL80 (Bemer et al, 2008;Portereiko et al, 2006;Steffen et al, 2008). In addition to other phenotypes, loss of RBR activity can also prevent fusion of polar nuclei and central cell differentiation (Johnston et al, 2010;Johnston et al, 2008).…”

Section: Wyrd Is Required Postfertilization For Endosperm Developmentmentioning

confidence: 99%

“…In Arabidopsis, core components of the splicing machinery are required for the maintenance of gametic versus accessory cell fate (Gross-Hardt et al, 2007;Moll et al, 2008). In addition, central cell fate depends on type I MADS-domain transcription factors (Bemer et al, 2008;Portereiko et al, 2006;Steffen et al, 2008), whereas a MADS target gene is necessary for the differentiation of accessory cells (Matias-Hernandez et al, 2010) and a MYB transcription factor for synergid differentiation (Kasahara et al, 2005). In maize, a LOB-domain transcription factor (Evans, 2007;Guo et al, 2004) and a diSUMO-like protein (Srilunchang et al, 2010) were shown to be involved in embryo sac differentiation.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Female gametophytic cell specification and seed development require the function of the putativeArabidopsisINCENP orthologWYRD

et al. 2011

View full text Add to dashboard Cite

SUMMARYIn plants, gametes, along with accessory cells, are formed by the haploid gametophytes through a series of mitotic divisions, cell specification and differentiation events. How the cells in the female gametophyte of flowering plants differentiate into gametes (the egg and central cell) and accessory cells remains largely unknown. In a screen for mutations that affect egg cell differentiation in Arabidopsis, we identified the wyrd (wyr) mutant, which produces additional egg cells at the expense of the accessory synergids. WYR not only restricts gametic fate in the egg apparatus, but is also necessary for central cell differentiation. In addition, wyr mutants impair mitotic divisions in the male gametophyte and endosperm, and have a parental effect on embryo cytokinesis, consistent with a function of WYR in cell cycle regulation. WYR is upregulated in gametic cells and encodes a putative plant ortholog of the inner centromere protein (INCENP), which is implicated in the control of chromosome segregation and cytokinesis in yeast and animals. Our data reveal a novel developmental function of the conserved cell cycle-associated INCENP protein in plant reproduction, in particular in the regulation of egg and central cell fate and differentiation.

show abstract

Section: Wyrd Is Required Postfertilization For Endosperm Developmentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Female gametophytic cell specification and seed development require the function of the putativeArabidopsisINCENP orthologWYRD

et al. 2011

View full text Add to dashboard Cite

show abstract

“…2 and Table 1) (reviewed by Masiero et al, 2011). For example, the M protein AGL80 and the M protein DIANA (DIA; AGL61) form a functional protein dimer and control the differentiation of the central cell (Portereiko et al, 2006;Bemer et al, 2008;Steffen et al, 2008). AGL80 is also expressed during endosperm development.…”

Section: Gametophyte Embryo and Seed Developmentmentioning

confidence: 99%

Developmental and evolutionary diversity of plant MADS-domain factors: insights from recent studies

et al. 2012

View full text Add to dashboard Cite

SummaryMembers of the MADS-box transcription factor family play essential roles in almost every developmental process in plants. Many MADS-box genes have conserved functions across the flowering plants, but some have acquired novel functions in specific species during evolution. The analyses of MADS-domain protein interactions and target genes have provided new insights into their molecular functions. Here, we review recent findings on MADS-box gene functions in Arabidopsis and discuss the evolutionary history and functional diversification of this gene family in plants. We also discuss possible mechanisms of action of MADS-domain proteins based on their interactions with chromatin-associated factors and other transcriptional regulators. Key words: MADS-box genes, Plant development, Evolution, Transcriptional regulationIntroduction MADS-domain transcription factors comprise one of the beststudied gene families in plants and members of this family play prominent roles in plant development. Two decades ago, the first MADS-box genes AGAMOUS (AG) from Arabidopsis thaliana (Yanofsky et al., 1990) and DEFICIENS (DEF) from Antirrhinum majus (Schwarz-Sommer et al., 1990) were discovered as regulators of floral organ identity. The sequence of the ~60 amino acid DNA-binding domains within these proteins showed striking similarities to that of the previously characterized proteins serum response factor (SRF) in Homo sapiens (Norman et al., 1988) and Minichromosome maintenance 1 (Mcm1) in Saccharomyces cerevisiae (Passmore et al., 1988). This shared and conserved domain was named the MADS domain (for MCM1, AG, DEF and SRF) and is present in all MADS-domain transcription factor family members (Schwarz-Sommer et al., 1990). Structural analysis of animal and yeast MADS domains showed that the N-terminal and central parts of the MADS domain make contacts with the DNA, while the C-terminal part of this domain contributes mainly to protein dimerization, resulting in a DNA-binding protein dimer consisting of two interacting MADS monomers (e.g. Pellegrini et al., 1995;Huang et al., 2000). Over the past 22 years, many MADS-box gene functions were uncovered in the model species Arabidopsis thaliana and in other flowering plants. Important model plant species for MADS-box gene research include snapdragon (Antirrhinum majus) (reviewed by Schwarz-Sommer et al., 2003), tomato (Solanum lycopersicum), petunia (Petunia hybrida) (Gerats and Vandenbussche, 2005), gerbera (Gerbera hybrida) (Teeri et al., 2006) and rice (Oryza sativa) (reviewed by Yoshida and Nagato, 2011).Initially, MADS-box genes were found to be major players in floral organ specification, but more recent studies revealed functions for MADS-box genes in the morphogenesis of almost all organs and throughout the plant life cycle, from embryo to gametophyte development. The MADS-box gene family in higher plants is significantly larger than that found in animals or fungi, with more than 100 genes in representative flowering plant Development 139, 3081-3098 (2012) REVIEW Box 1...

show abstract

“…Furthermore, it is expressed in microspores (Parenicová et al, 2003), but reciprocal crosses excluded a vital role for male gametophyte development. By RT-PCR experiments, AGL80 transcripts were detected in most organs (roots, stems, leaves, flowers, and anthers); therefore, weak alleles or inducible silencing strategies might be useful to shed light on other functions that AGL80 might have during development.Yeast two-hybrid assays showed that AGL80 interacts with the Ma-type MADS domain protein AGL61, named DIANA (DIA; de Folter et al, 2005;Bemer et al, 2008;Steffen et al, 2008). DIA/ AGL61 contains a distinct N-terminal region in front of the MADS domain, thus being different from most of the Ma proteins, where the MADS domain is located close to the N terminus.…”

mentioning

confidence: 99%

The Emerging Importance of Type I MADS Box Transcription Factors for Plant Reproduction

et al. 2011

View full text Add to dashboard Cite

Based on their evolutionary origin, MADS box transcription factor genes have been divided into two classes, namely, type I and II. The plant-specific type II MIKC MADS box genes have been most intensively studied and shown to be key regulators of developmental processes, such as meristem identity, flowering time, and fruit and seed development. By contrast, very little is known about type I MADS domain transcription factors, and they have not attracted interest for a long time. A number of recent studies have now indicated a key regulatory role for type I MADS box factors in plant reproduction, in particular in specifying female gametophyte, embryo, and endosperm development. These analyses have also suggested that type I MADS box factors are decisive for setting reproductive boundaries between species. MADS DOMAIN ENCODING GENESMADS box genes are of ancient origin and are found in animals, fungi, and plants. All identified MADS box genes encode a highly conserved N-terminal DNA binding domain 55 to 60 amino acids in length named the MADS domain ( Figure 1; Trö bner et al., 1992). Homology searches in the nonredundant microbial database using a Hidden Markov Model for seed alignment of the MADS domain suggested that the MADS domain originates from the DNA binding subunit A of topoisomerases IIA subunit A (Gramzow et al., 2010).The acronym MADS ) is derived from the initials of MINICHROMOSOME MAINTENANCE1 (MCM1, Saccharomyces cerevisiae; Passmore et al., 1988), AGAMOUS (Arabidopsis thaliana; Yanofsky et al., 1990), DEFI-CIENS (Antirrhinum majus; Sommer et al., 1990), and SERUM RESPONSE FACTOR (SRF, Homo sapiens; Norman et al., 1988). These members of the MADS box gene family play important biological roles; for example, the human SRF coordinates the transcription of the proto-oncogene c-fos (Masutani et al., 1997;Mo et al., 2001), while MCM1 is central to the transcriptional control of cell type-specific genes and the pheromone response in the yeast S. cerevisiae (Shore and Sharrocks, 1995;Mead et al., 2002).Plant MADS box genes were first identified as regulators of floral organ identity and have since been reported to control additional developmental processes, such as the determination of meristem identity of vegetative, inflorescence, and floral meristems, root growth, ovule and female gametophyte development, flowering time, fruit ripening, and dehiscence (Zhang and Forde, 1998;Ng and Yanofsky, 2001;Giovannoni, 2004;Whipple et al., 2004;Liu et al., 2009). Studies using several model species, including Arabidopsis, A. majus, Petunia hybrida, Zea mays, and Oryza sativa, have revealed that many of these functions are conserved among angiosperms (Schwarz-Sommer et al., 2003;Vandenbussche et al., 2003;Kater et al., 2006). ARABIDOPSIS MADS BOX TYPE I AND TYPE II: AN EVOLUTIONARY OVERVIEWBased on sequence conservation in the MADS domain, these transcription factors can be grouped into two main lineages, named type I (SRF-like) and type II (MEF2-like; Alvarez-Buylla et al., 2000). In animals, type I genes are involv...

show abstract

AGL61 Interacts with AGL80 and Is Required for Central Cell Development in Arabidopsis

Cited by 132 publications

References 42 publications

Female gametophytic cell specification and seed development require the function of the putativeArabidopsisINCENP orthologWYRD

Female gametophytic cell specification and seed development require the function of the putativeArabidopsisINCENP orthologWYRD

Developmental and evolutionary diversity of plant MADS-domain factors: insights from recent studies

The Emerging Importance of Type I MADS Box Transcription Factors for Plant Reproduction

Contact Info

Product

Resources

About