Agreement between Scheimpflug Camera and the Swept-source Optical Coherence Tomography Measurements in Keratometry and Higher-order Aberrations

Abstract

To evaluate the compatibility of corneal curvature and astigmatism, and higher-order aberrations (HOAs) measured by the Scheimpflug camera Pentacam HR and the swept-source optical coherence tomography ANTERION.Method: This prospective study included normal subjects with no ophthalmic history. Steep keratometry (K), flat K, astigmatism and its axis of the anterior and posterior surfaces, total corneal power, and HOAs using the two instruments were compared. To compare the mean values of the measurements, a paired t-test was used. Bland-Altman analysis was applied to assess the agreement between the two devices.Results: Fifty-three eyes of 53 subjects were evaluated. There were statistically significant differences for steep K, astigmatism, and vector J0, J45 in the anterior surface and total corneal power between the two devices (p<0.05). There were also significant differences in the most of the keratometric values of the posterior corneal surface (p<0.05) except J0 (p=0.410). Both devices showed strong positive correlations in Ks, Kf, Kastig (r>0.81, p<0.001) with wide ranges of a 95% limit of agreement (LoA). Vectoral components were significantly correlated (r>0.78, p<0.001) with narrow 95% LoA, except J45 of the posterior surface (r=0.39, p=0.004). In the corneal HOAs, there were statistically significant differences in the vertical coma, horizontal trefoil, spherical aberration, and root mean square (RMS) of each fifth-and sixth-order Zernike coefficient (p=0.043, 0.041, p<0.001, p<0.001, and p<0.001, respectively). Other HOAs showed moderate to strong positive correlations (r>0.37, p<0.05). Most HOAs, except for the horizontal trefoil, showed clinically acceptable agreements. The total RMS of HOAs was not significantly different between the two devices (p=0.122). Conclusion:Most of the keratometric values cannot be used interchangeably. However, the vectoral component of astigmatism showed clinically good agreement. Several HOAs have statistically significant differences; however, almost all HOAs showed acceptable agreements, except for the horizontal trefoil.

Repeatability and agreement of two swept-source optical coherence tomographers and Scheimpflug imaging for measurements of corneal curvature

“…Similar results were obtained in the present study with LoA of -0.03 to 0.86 D between Anterion and CASIA2. Gim et al [12] showed good agreement between Anterion and Pentacam for at and steep TCP with the maximum absolute LoA ≤ 0.61 D, which were close to our results with the maximum absolute LoA ≤ 0.48 D.…”

“…-0.3643 to 0.5069 D for at sim-K; LoA: -0.3705 to 0.5638 D for steep sim-K) 13 . Flat and steep sim-K showed good agreement between Anterion and Pentacam in the study by Gim et al [12] with the maximum absolute LoA ≤ 0.50 D. Similar results were obtained in the current study, good agreement was acquired for both at and steep sim-K between Anterion and Pentacam with LoA of -0.18 to 0.48 D and − 0.36 to 0.40 D, respectively.…”

“…[22]. Gim et al [12] reported the LoA of -0.56 to 0.23 D between Anterion and CASIA2 for TCA. We detected the maximum absolute LoA D ≥ 0.66 D between the three devices in the present study.…”

“…Several recently published studies have investigated the differences and agreement of corneal curvature between Pentacam and CASIA2 [9,10]. Other research have compared Pentacam with Anterion for keratometry [11,12]. To our knowledge, no study has compared Anterion, Pentacam, and CASIA2 for corneal curvature simultaneously.…”

Corneal Higher-Order Aberrations Measurements: Precision of SD-OCT/Placido Topography and Comparison with a Scheimpflug/Placido Topography in Eyes After Small-Incision Lenticule Extraction

“…No studies are currently evaluating the agreement between MS-39 measurements of corneal aberrations and those by other devices. Recent studies have reported agreement between the Anterion and Pentacam HR devices for corneal aberrations in healthy subjects [36,37]. Pe ´rez-Bartolome ´et al [36] indicated that vertical coma and RMS HOA values had good agreement, as the 95% LoAs ranged from -0.37 to 0.308 lm and from -0.27 to 0.305 lm, respectively.…”