Agreement to detect glaucomatous visual field progression by using three different methods: a multicentre study

Abstract

AimTo examine the level of agreement among nine clinicians in assessing progressive deterioration in visual field (VF) overview using three different methods of analysis. Methods Each visual field was assessed by Humphrey Field Analyzer (HFA), program 24-2 SITA Standard. Nine expert clinicians assessed the progression status of each series by using HFA 'overview printouts' (HFA OP), the Guided Progression Analysis (GPA) and the Guided Progression Analysis (GPA2). VF series were presented in random order, but each patient's VF remained in chronological order within a given field series. Each clinician adopted his personal methods based on his knowledge to evaluate VF progression. The level of agreement between the clinicians was evaluated by using weighted k statistics.Results A total of 303 tests, comprising 38 visual field series of 7.963.4 tests (mean6SD), were assessed by the nine glaucoma specialists. When the intra-observer agreement was evaluated between HFA OP and GPA, the mean k statistic was 0.5860.13, between HFA OP and GPA2, k was 0.5560.06 and between GPA and GPA2 it was 0.5660.17. When the inter-observer agreement was analysed k statistic was 0.65 for HFA OP, 0.54 for GPA and 0.70 for GPA2. Conclusions Using any procedure for evaluating the progression of a series of VF, agreement between expert clinicians is moderate. Clinicians had higher agreement when GPA2 was used, followed by HFA OP and GPA printouts, but these differences were not significant.

Glaucoma Progression Analysis Software Compared with Expert Consensus Opinion in the Detection of Visual Field Progression in Glaucoma

“…28 They reported a median kappa of 0.58 for intra-observer agreement between the session when only the overview printout was available and the session when only the GPA 1 printout was available. They did not report the level of agreement among the expert readers' opinions and the GPA result itself.…”

Detection of Early Glaucomatous Progression With Octopus Cluster Trend Analysis

“…4,5 However, most of the current information on the value of software-provided detection of progression comes from the former instrument family. [6][7][8][9][10] The commercially available Octopus software versions (Peritrend, EyeSuite) offer determination of the rate of progression for global mean defect (MD), diffuse defect (DD), local defect, and pointwise linear regression analysis. 11 However, as several core technical features (background luminance, stimulus duration, number and distribution of the test points, and size of the tested central visual field) are different in the Octopus perimeters and Humphrey Field Analyzers, 4,5 experience on progression determined with the Humphrey system cannot be directly applied to Octopus perimetry.…”

Validity and reliability of eye healthcare professionals in the assessment of glaucoma - a systematic review

“…A review of reference lists of included full text articles revealed another four articles for inclusion. Three studies which were originally included for data extraction were excluded on closer inspection . Asakawa et al.…”