2024
DOI: 10.3389/fonc.2024.1441235
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AGTR1: a potential biomarker associated with the occurrence and prognosis of lung adenocarcinoma

Rui Xiao,
Jiajia Han,
Yongjian Deng
et al.

Abstract: IntroductionLung adenocarcinoma, a disease with complex pathogenesis, high mortality and poor prognosis, is one of the subtypes of lung cancer. Hence, it is very crucial to find novel biomarkers as diagnostic and therapeutic targets for LUAD.MethodsGSE10072 was used for DEGs and WGCNA, and the intersection genes were subjected to enrichment analysis through Metascape and GSEA. Key genes were screened by three machine learning methods. Further, the reliability of key genes was identified by ROC, COX regression … Show more

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