AIDS presenting as primary testicular lymphoma

Armenakas, Noel A.; Schevchuk, Maria M.; Brodherson, Michael; Fracchia, John A.

doi:10.1016/0090-4295(92)90519-3

Cited by 24 publications

(4 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…97 If a primary B-cell lymphoma is found in a person younger than 50, it implies compromised immunologic status, most likely, AIDS. 98 The most common presenting symptom is testicular enlargement 97 and bilateral testicular masses also suggest the diagnosis. Histopathologically, diffuse histiocytic lymphoma is seen.…”

Section: Lymphomamentioning

confidence: 99%

Urologic Problems in Patients with Acquired Immunodeficiency Syndrome

Staiman

Lowe

2004

The Scientific World JOURNAL

View full text Add to dashboard Cite

show abstract

Section: Lymphomamentioning

confidence: 99%

Urologic Problems in Patients with Acquired Immunodeficiency Syndrome

Staiman

Lowe

2004

The Scientific World JOURNAL

View full text Add to dashboard Cite

show abstract

“…AIDS patients often suffer from orchitis, hypogonadism, oligospermia, or azoospermia (20,100,253,257,325) and, in some cases, from testicular germ cell tumor or lymphoma (54,116,244,351). Among 3,015 HIV-positive men, the incidence of testis tumors has been reported to be 0.2%, which is 57 times that of US.…”

Section: The Human Testismentioning

confidence: 99%

Viruses in the Mammalian Male Genital Tract and Their Effects on the Reproductive System

Dejucq

Jégou

2001

Microbiol Mol Biol Rev

289

220

View full text Add to dashboard Cite

This review describes the various viruses identified in the semen and reproductive tracts of mammals (including humans), their distribution in tissues and fluids, their possible cell targets, and the functional consequences of their infectivity on the reproductive and endocrine systems. The consequences of these viral infections on the reproductive tract and semen can be extremely serious in terms of organ integrity, development of pathological and cancerous processes, and transmission of diseases. Furthermore, of essential importance is the fact that viral infection of the testicular cells may result not only in changes in testicular function, a serious risk for the fertility and general health of the individual (such as a fall in testosteronemia leading to cachexia), but also in the possible transmission of virus-induced mutations to subsequent generations. In addition to providing an exhaustive account of the data available in these domains, this review focuses attention on the fact that the interface between endocrinology and virology has so far been poorly explored, particularly when major health, social and economical problems are posed. Our conclusions highlight the research strategies that need to be developed. Progress in all these domains is essential for the development of new treatment strategies to eradicate viruses and to correct the virus-induced dysfunction of the endocrine system

show abstract

“…Concerning germ cell tumors, Wilson prefers an instant aggressive treatment with retroperitoneal lymphadenectomy (whether or not combined with chemotherapy) to avoid the risk of recurrence. In fact, tumor relapses will be difficult to control in the progressive stages of immunodefi ciency syndrome.Several recent reports focus on the abnormally fre quent appearance of testicular tumors in patients suffer ing from AIDS [1,2], considering that so far, the genito urinary apparatus had seemed spared or mainly subject to infections [3], Nineteen tumors, either germ cell tumors [1,2, 4-6] or lymphomas [1,[7][8][9], have been mentioned in the litera ture. These tumors, as a result of acquired immunodefi ciency, are rather atypical in both their diagnosis and evo lution.…”

mentioning

confidence: 99%