AIEgens functionalized gadolinium-based aminoclay as dual-modal probes for fluorescence and magnetic resonance imaging

Li, Dongdong; Song, Wenzhi; Wang, Dezhou; Qi, Shengyang; Li, Kaishen; Yin, Wen

doi:10.1016/j.inoche.2018.07.003

Cited by 4 publications

(4 citation statements)

References 19 publications

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“…Although fluorescence imaging has the advantages of noninvasive detection and real‐time monitoring, it is still limited by insufficient tissue penetration depth. Therefore, developing multimodal nanoprobes combined with fluorescence and other imaging methods has become a rapidly growing field . Computed tomography possesses the advantage of unlimited penetration depth, but its sensitivity is low .…”

Section: Applications Of Aie Probes In the Field Of Biological Sciencementioning

confidence: 99%

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A new approach to developing diagnostics and therapeutics: Aggregation‐induced emission‐based fluorescence turn‐on

Guo

Song

et al. 2019

Medicinal Research Reviews

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Fluorescence imaging is a promising visualization tool and possesses the advantages of in situ response and facile operation; thus, it is widely exploited for bioassays. However, traditional fluorophores suffer from concentration limits because they are always quenched when they aggregate, which impedes applications, especially for trace analysis and real‐time monitoring. Recently, novel molecules with aggregation‐induced emission (AIE) characteristics were developed to solve the problems encountered when using traditional organic dyes, because these new molecules exhibit weak or even no fluorescence when they are in free movement states but emit intensely upon the restriction of intramolecular motions. Inspired by the excellent performances of AIE molecules, a substantial number of AIE‐based probes have been designed, synthesized, and applied to various fields to fulfill diverse detection tasks. According to numerous experiments, AIE probes are more practical than traditional fluorescent probes, especially when used in bioassays. To bridge bioimaging and materials engineering, this review provides a comprehensive understanding of the development of AIE bioprobes. It begins with a summary of mechanisms of the AIE phenomenon. Then, the strategies to realize accurate detection using AIE probes are discussed. In addition, typical examples of AIE‐active materials applied in diagnosis, treatment, and nanocarrier tracking are presented. In addition, some challenges are put forward to inspire more ideas in the promising field of AIE‐active materials.

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Section: Applications Of Aie Probes In the Field Of Biological Sciencementioning

confidence: 99%

“…Therefore, developing multimodal nanoprobes combined with fluorescence and other imaging methods has become a rapidly growing field. 121 Computed tomography possesses the advantage of unlimited penetration depth, but its sensitivity is low. 122…”

Section: Diagnosis Based Upon the Aie Imaging Of The Lesionmentioning

confidence: 99%

A new approach to developing diagnostics and therapeutics: Aggregation‐induced emission‐based fluorescence turn‐on

Guo

Song

et al. 2019

Medicinal Research Reviews

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“…The obtained F-AC was successfully applied for fluorescence and magnetic resonance imaging. [17] Europium (III) complexes were also functionalized AC to form red-emitting F-AC through noncovalently assembled approaches. The as-prepared F-AC exhibited good photostability and thermostability.…”

mentioning

confidence: 99%

“…including bioimaging, [16,17] drug delivery, [18] sensors, [19] photoelectric devices, [20] and so on. Therefore, many strategies have been proposed for the synthesis of F-AC with different emissions.…”

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confidence: 99%

Facile one‐pot synthesis of fluorescent aminoclay and the applications for fluorescence sensing Cr₂O₇²⁻

Guo

Shi

et al. 2022

Luminescence

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Here, we developed a facile one-pot strategy for the fabrication of fluorescent aminoclay (F-AC) through in situ solvothermal treatment of 3-aminopropyltrimethoxysilane, MgCl 2 , and sodium ascorbate at 180 C for 6 h. The obtained F-AC exhibited blue emission, good water solubility, and satisfactory photostability. It was observed that Cr 2 O 7 2À could selectively quench the fluorescence of F-AC through the inner filter effect and static quenching process.As a result, a novel fluorescent F-AC-based nanosensor was constructed with good linearity in the range 0.1-75 μM. The nanosensor was successfully applied in real water samples with satisfactory results. This work not only provides a novel nanosensor for Cr 2 O 7 2À , but also highlights the F-AC's promising applications in wider fields due to the versatility and simplicity of the preparation strategy.applications, Cr 2 O 7 2À , fluorescent aminoclay, fluorescent detection, one-pot synthesis | INTRODUCTIONHexavalent chromium (Cr(VI)) is widely used in many fields including electroplating, organic synthesis, leather tanning, textile dying, printing, steel manufacturing, etc. [1][2][3] However, Cr(VI) exhibits highly harmful, teratogenic, and potentially carcinogenic effects on living systems. Low concentrations of Cr(VI) may contribute to kidney failure and rhinitis. [4] The long-term intake of Cr(VI) can damage the DNA of organisms and induce lung adenocarcinoma, respiratory system damage, genetic defects, and so on. [5,6] Importantly, Cr(VI) in water or soil can be enriched in crops and the human body via the food chain, directly or indirectly leading to dangerous effects on human health and the environment. [7] Therefore, the detection of Cr(VI) is of great significance.To date, various approaches have been developed for sensing Cr(VI), [3] such as atomic absorption spectrum, [8] inductively coupled plasma mass spectrum (ICP-MS), [9] electrochemical methods, [10,11] ion chromatography, [12] colorimetry, [13] fluorescence, [6,14] and so on. Among these detection strategies, these traditional instrumental methods suffer from complicated operation and high costs. In contrast, optical methods including colorimetry and fluorescence provide simple, facile approaches for sensing Cr(VI) due to their simple operation and fast response. We prepared yellow-emissive nitrogen and boron-doped carbon quantum dots, and the prepared carbon quantum dots were successfully applied for fluorescence detection of Cr(VI). [6] Chen and co-workers presented a fluorescence enhancement method for sensing Cr(VI) using N-and S-doped carbon dots. [14] Tannic acid-stabilized fluorescent copper nanoclusters have been synthesized for fluorescence turn-off detection of Cr(VI) with a linear range 0.03-60 μM. [15] These methods provide promising paths for sensing Cr(VI). However, novel detection systems for sensing Cr(VI) are still required.Fluorescent aminoclay (F-AC) is a new type of fluorescent nanomaterial that has attracted considerable attention due to its unique optical properties, easy f...

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Fabrication of claviform fluorescent polymeric nanomaterials containing disulfide bond through an efficient and facile four-component Ugi reaction

Huang

Jiang

et al. 2021

Materials Science and Engineering: C

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AIEgens functionalized gadolinium-based aminoclay as dual-modal probes for fluorescence and magnetic resonance imaging

Cited by 4 publications

References 19 publications

A new approach to developing diagnostics and therapeutics: Aggregation‐induced emission‐based fluorescence turn‐on

A new approach to developing diagnostics and therapeutics: Aggregation‐induced emission‐based fluorescence turn‐on

Facile one‐pot synthesis of fluorescent aminoclay and the applications for fluorescence sensing Cr₂O₇²⁻

Fabrication of claviform fluorescent polymeric nanomaterials containing disulfide bond through an efficient and facile four-component Ugi reaction

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AIEgens functionalized gadolinium-based aminoclay as dual-modal probes for fluorescence and magnetic resonance imaging

Cited by 4 publications

References 19 publications

A new approach to developing diagnostics and therapeutics: Aggregation‐induced emission‐based fluorescence turn‐on

A new approach to developing diagnostics and therapeutics: Aggregation‐induced emission‐based fluorescence turn‐on

Facile one‐pot synthesis of fluorescent aminoclay and the applications for fluorescence sensing Cr2O72−

Fabrication of claviform fluorescent polymeric nanomaterials containing disulfide bond through an efficient and facile four-component Ugi reaction

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Facile one‐pot synthesis of fluorescent aminoclay and the applications for fluorescence sensing Cr₂O₇²⁻