Aiming to personalized laser therapy for nevus of Ota: melanin distribution dependent parameter optimization

Xiao, Chunyang; Sang, Xuehao; Liu, Dong; Chen, Bin; Deng, Chenggang; Wang, Jiafeng

doi:10.1007/s10103-022-03673-2

Cited by 2 publications

(1 citation statement)

References 34 publications

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“…Nevus of Ito and congenital dermal melanocytosis are similar, occurring on the upper trunk and shoulder, and lower back, respectively. Both 1064 and 755 nm quality-switched (Q-switched) lasers have shown benefit in treatment of skin types III-IV, using nanometer pulse durations to target melanin particles [21,22]. 1064 nm Q-switched Nd : YAG has also been shown to be well tolerated and effective in skin types V and VI, although there is risk of guttate hypopigmentation [23].…”

Section: Nevus Of Ota/dermal Melanocytosismentioning

confidence: 99%

Update on lasers in pediatric dermatology: how primary care providers can help patients and families navigate appropriate treatment options and timelines

Osborn

Nieman

2023

Current Opinion in Pediatrics

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Purpose of review The use of lasers in pediatric dermatology is well established, but recent literature has expanded the evidence for specific timelines of treatment. Additionally, new devices and combinations with medical therapy have improved outcomes and treatment options for various conditions. Recent findings Pulsed dye laser remains the first-line laser for vascular lesions. Recent guidelines support early initiation of laser treatment in port-wine birthmarks to optimize outcomes. For hemangiomas, laser treatment can offer a meaningful addition to oral propranolol therapy. Lasers with shorter wavelengths offer improved outcomes with decreased downtime for pigmented lesions. General anesthesia in the pediatric population continues to be a controversial topic, and the decision to perform laser under general versus topical anesthesia requires discussion with family of risks and benefits. Summary Primary care providers can benefit their patients by prompt referral to dermatology for discussion of laser treatment. Port-wine birthmarks require referral in the first weeks of life so that laser treatment can be initiated if appropriate. Although many dermatologic conditions cannot be completely cleared or cured with laser, treatment can offer meaningful outcomes and benefit for patients and families.

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Section: Nevus Of Ota/dermal Melanocytosismentioning

confidence: 99%

Update on lasers in pediatric dermatology: how primary care providers can help patients and families navigate appropriate treatment options and timelines

Osborn

Nieman

2023

Current Opinion in Pediatrics

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Patchy Dermal Melanocytosis: Differential Diagnosis and Management

Zhu,

Cen,

Chang

et al. 2024

J of Cosmetic Dermatology

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BackgroundNevus of Ito and Mongolian spots are distinct clinical presentations of patchy dermal melanocytosis, characterized by similar dermatological manifestations that can pose diagnostic difficulties for clinicians.AimThis review aims to consolidate current understanding and research advancements on these conditions to facilitate clinical diagnosis, differential diagnosis, and management.MethodsA comprehensive search of databases including PubMed and Google Scholar was conducted, along with an analysis of pertinent literature retrieved from reference lists spanning nearly four decades.ResultsEpidemiological, clinical, and pathological profiles exhibit nuanced differences between the two conditions, with unique expressions under electron microscopy and the regression possibility. It is noteworthy that most Mongolian spots naturally fade with advancing age, in contrast to nevus of Ito, which persist and may potentially evolve into malignant lesions. While picosecond laser treatment has shown greater efficacy than nanosecond lasers, the lower‐energy approach holds particular promise in pediatric cases. The therapeutic landscape for patchy dermal melanocytosis is evolving, shifting from selective photothermal action to photomechanical or subcellular photothermal modalities.ConclusionThis review underscores the importance of meticulous clinical assessment and the potential of innovative therapeutic approaches in managing these conditions.

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Aiming to personalized laser therapy for nevus of Ota: melanin distribution dependent parameter optimization

Cited by 2 publications

References 34 publications

Update on lasers in pediatric dermatology: how primary care providers can help patients and families navigate appropriate treatment options and timelines

Update on lasers in pediatric dermatology: how primary care providers can help patients and families navigate appropriate treatment options and timelines

Patchy Dermal Melanocytosis: Differential Diagnosis and Management

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