Airborne Contact Dermatitis Caused by Essential Oils in a Child

Shah, Kishan M.; Goldman, Shauna; Agim, Nnenna G.

doi:10.1097/der.0000000000000430

Cited by 10 publications

(6 citation statements)

References 4 publications

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“…These can cross-react with essential oils, though if essential oil allergy is suspected, patch testing with the patient's own products, either directly or in diluted form, should be performed. 43,44 Patients sensitized to colophony, a tree resin, and propolis (beeswax) that is derived from tree bark can display cross-reactivity with fragrance mixes on patch testing, though the inverse may not be true. 45 Balsam of Peru is also a tree-derived liquid, which contains the antigenic compounds benzyl benzoate and benzyl cinnamate, cinnamic aldehyde, cinnamic alcohol, eugenol, isoeugenol, and vanillin, which can be cross-reactive with spices, such as cloves.…”

Section: Fragrancesmentioning

confidence: 99%

“…These fragrances can oxidize on exposure to air, such as with sprayed perfumes, and essential oil diffusers, which have become increasingly popular through social media, are sources of potentiated allergen. 44 Essential oil allergy may not be detected through standard patch test screening using fragrance mixes and may require patch testing with the patient's product. 43,44 Excipients PG PG comprised a propane molecule with a hydroxyl group at position 1 and 2.…”

Section: Fragrancesmentioning

confidence: 99%

“…44 Essential oil allergy may not be detected through standard patch test screening using fragrance mixes and may require patch testing with the patient's product. 43,44 Excipients PG PG comprised a propane molecule with a hydroxyl group at position 1 and 2. 46 It has strong water-attracting properties, and as such, is a humectant often used as a vehicle for topical medications that can help increase the bioavailability of the drug being delivered.…”

Section: Fragrancesmentioning

confidence: 99%

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A review of contact dermatitis

Brar¹

2021

Annals of Allergy, Asthma & Immunology

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Nickel is the most common allergen, though many other sources of contact allergens are hidden in everyday products, such as preservatives and fragrances. In screening for contact allergy, it is important to inquire about environmental and occupational exposures, including wet work and mechanisms of irritation, such as frequent hand washing or wiping. The mechanisms of contact dermatitis are complex and may involve different T cell signaling pathways. Patch testing is required for diagnosis, and patch testing with patient's personal products is recommended. Management currently focuses on allergen avoidance, topical therapies, or corticosteroids; some biologics may be indicated for treatment.

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Section: Fragrancesmentioning

confidence: 99%

Section: Fragrancesmentioning

confidence: 99%

Section: Fragrancesmentioning

confidence: 99%

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A review of contact dermatitis

Brar¹

2021

Annals of Allergy, Asthma & Immunology

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“…Darüber hinaus kann auch die verdampfte Flüssigkeit ACD hervorrufen, wie in einem Fall aus Portugal, in dem Menthol das auslösende Allergen war [90]. Die Verdampfung wird auch durch mit ätherischen Ölen gefüllte Diffusoren erreicht, von denen bereits bekannt ist, dass sie bei Exponierten eine ACD auslösen können – wie im kürzlich beschriebenen Fall eines 7-jährigen Kindes, bei dem im Zusammenhang mit Lin-OOHs eine aerogene ACD auftrat (Reaktion im Epikutantest +++) [91]. Die inhärente Flüchtigkeit von Duftstoffen kann zu unerwarteter Diffusion führen, wie der Fall eines 82-jährigen Patienten zeigt, der seinen Stomabeutel mit einem Duftspray desodorierte.…”

Section: Ergebnisseunclassified

Kontaktallergien – Neu aufkommende Allergene und Auswirkungen für das Gesundheitswesen

Uter¹,

Werfel

Lepoittevin

et al. 2021

Kompass Dermatol

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Kontaktallergie (Sensibilisierung) und daraus resultierende allergische Kontaktdermatitis (ACD) sind von erheblicher Tragweite aus Sicht des Gesundheitswesens. Für die vorliegende Übersichtsarbeit hierzu wurden alle passenden Artikel aus dem Zeitraum 2018–2019 per systematischer Suche in Medline und Web of Science<sup>TM</sup> ermittelt; außerdem wurden alle verfügbaren Ausgaben der Fachzeitschriften „Contact Dermatitis“ und „Dermatitis“ manuell durchsucht und so eine frühere, ähnliche Übersichtsarbeit fortgeschrieben und neu fokussiert. Neue Allergene ebenso wie bekannte Allergene, die in neuem Expositionskontext gefunden wurden oder deren Bedeutung in sonstiger Hinsicht neu bewertet wurde, werden in Abschnitten nach Substanzklasse gegliedert beschrieben (z. B. Metalle, Konservierungsmittel, Duftstoffe). Als gemeinsames Ergebnis zahlreicher Untersuchungen fällt sowohl ein Mangel an Informationen über die Produktzusammensetzung auf, z. B. in Bezug auf ein neu beschriebenes Allergen in Leinenturnschuhen (Dimethylthiocarbamylbenzothiazolsulfid), als auch vor allem die mangelnde Kooperativität von Herstellern von Blutzuckermessgeräten bzw. Insulinpumpen. Zu den letztgenannten Geräten hat eine internationale Zusammenarbeit zwischen Dermatologen und Chemikern gezeigt, dass sie bei zahlreichen Diabetikern schwere ACD verursachen, indem sie Isobornylacrylat bzw. N,N’-Dimethylacrylamid freisetzen. Eine verbesserte und vollständige Deklaration der Inhaltsstoffe für Produkte alle Art – und nicht nur, wie wir es derzeit in Europa haben, bei Kosmetika (abgesehen von der vollständigen Auflistung der Duftstoffe) – muss auf die legislative Agenda gesetzt werden.

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“…Furthermore, the vaporised liquid may also cause ACD, as in the case from Portugal, where menthol was the culprit allergen [90]. Vaporisation is also achieved by diffusers filled with essential oils, which has been previously reported to cause ACD in the exposed; recently, a 7-year-old child has been described who developed airborne ACD related to Lin-OOHs (+++ reaction in patch testing) [91]. The volatility of fragrances inherent in their nature may lead to unexpected diffusion, as illustrated by a 82-year-old patient who deodorised his stoma bag by use of a scented spray.…”

Section: Fragrancesmentioning

confidence: 99%

Contact Allergy—Emerging Allergens and Public Health Impact

Uter

Werfel

Lepoittevin

et al. 2020

IJERPH

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Contact allergy (sensitisation) and allergic contact dermatitis (ACD) resulting from it have a considerable public health impact. For the present review, all pertinent articles were systematically searched via Medline and Web of Science™; additionally, all available issues of the journals “Contact Dermatitis” and “Dermatitis” were manually searched, covering the years 2018–2019, thereby extending and re-focusing a previous similar review. New allergens, or previously described allergens found in a new exposure context or of other current importance, are described in sections according to substance classes, e.g., metals, preservatives, fragrances. As a common finding in many investigations, a lack of information on product composition has been noted, for instance, regarding a newly described allergen in canvas shoes (dimethylthiocarbamylbenzothiazole sulfide) and, most notably, absence of co-operation from manufacturers of glucose-monitoring devices and insulin pumps, respectively. These latter devices have been shown to cause severe ACD in a considerable number of diabetic patients caused by the liberation of isobornyl acrylate and N,N’-dimethylacrylamide, respectively, as demonstrated by an international collaboration between dermatologists and chemists. Improved and complete ingredient labelling for all types of products, and not just as we have with cosmetics at present (apart from full listing of fragrance substances) in Europe, must be put on the legislative agenda.

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Airborne Contact Dermatitis Caused by Essential Oils in a Child

Cited by 10 publications

References 4 publications

A review of contact dermatitis

A review of contact dermatitis

Kontaktallergien – Neu aufkommende Allergene und Auswirkungen für das Gesundheitswesen

Contact Allergy—Emerging Allergens and Public Health Impact

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