Aktivitas pegagan (Centella asiatica) pada dermatologi

Fernenda, Larysa; Ramadhani, Arba Pramundita; Syukri, Yandi

doi:10.25077/jsfk.9.3.237-244.2022

Cited by 3 publications

(2 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Saponins make up approximately 1-8% of the total gotu kola ingredients. Ursane-and oleanane-type pentacyclic triterpenoid saponins are primary centellosides (Fernenda et al, 2022). Alkaloids, saponins, tannins, flavonoids, steroids, and triterpenoids are components of gotu kola plants that are used as active ingredients in cosmetic preparations (Juliadi & Juanita, 2002;Sutardi, 2016).…”

Section: Introductionmentioning

confidence: 99%

Untitled

2024

View full text Add to dashboard Cite

Acne is an inflammatory skin condition caused by sebaceous follicles and characterized by skin inflammation in the form of a buildup of bacteria and oil that clogs pores and causes acne. Centella asiatica (L.) Urb., often known as gotu kola, has antibacterial properties that inhibit Propionibacterium acnes, thereby reducing papules, pustules, and nodules. Antioxidants, asiatic acid, and madecassic acid found in gotu kola (Centella asiatica (L.) Urb.) can treat wounds. Skin damaged by acne can be repaired and rejuvenated with gotu kola antioxidants, which also help collagen formation more quickly in the skin. This research aims to examine the ability of gotu kola (Centella asiatica (L.) Urb.) extract to inhibit acnecausing bacteria (Propionibacterium acnes) resulting from a literature review. This research method is a literature review or literature review. Research journals that met the inclusion criteria (activity test results suppressing bacterial growth activity) were collected, and a journal summary was made. A summary of the research journals is included in the table sorted by the year of publication of the journal. Based on the results of a literature review carried out by researchers, Gotu kola can be extracted using the maceration method by soaking the plant material in an extraction solvent such as ethanol or water for a specified time. This process was used to remove the active components from the plant material. The inhibition zone formed was evaluated to determine the effectiveness of the extracts or preparations containing gotu kola extract in preventing bacterial growth. Antibacterial power was tested using agar media inoculated with Propionibacterium acnes, and extracts or preparations were added using the diffusion method. From the literature review, it can be concluded that antioxidants and other bioactive substances contained in gotu kola extract can inhibit the growth of Propionibacterium acnes. This was shown based on the negative control not suppressing bacterial growth activity, while the cream containing gotu kola extract at a concentration of 5% had an inhibitory power of 17.3 mm.

show abstract

Section: Introductionmentioning

confidence: 99%

Untitled

2024

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

REVIEW: A STUDY ON THE USE OF GOTU KOLA EXTRACT (Centella asiatica (L.) Urb.) AS A TREATMENT FOR ACNE

Ikasari,

Pebriani

2024

View full text Add to dashboard Cite

Acne is an inflammatory skin condition caused by sebaceous follicles and characterized by skin inflammation in the form of a buildup of bacteria and oil that clogs pores and causes acne. Centella asiatica (L.) Urb., often known as gotu kola, has antibacterial properties that inhibit Propionibacterium acnes, thereby reducing papules, pustules, and nodules. Antioxidants, asiatic acid, and madecassic acid found in gotu kola (Centella asiatica (L.) Urb.) can treat wounds. Skin damaged by acne can be repaired and rejuvenated with gotu kola antioxidants, which also help collagen formation more quickly in the skin. This research aims to examine the ability of gotu kola (Centella asiatica (L.) Urb.) extract to inhibit acne-causing bacteria (Propionibacterium acnes) resulting from a literature review. This research method is a literature review or literature review. Research journals that met the inclusion criteria (activity test results suppressing bacterial growth activity) were collected, and a journal summary was made. A summary of the research journals is included in the table sorted by the year of publication of the journal. Based on the results of a literature review carried out by researchers, Gotu kola can be extracted using the maceration method by soaking the plant material in an extraction solvent such as ethanol or water for a specified time. This process was used to remove the active components from the plant material. The inhibition zone formed was evaluated to determine the effectiveness of the extracts or preparations containing gotu kola extract in preventing bacterial growth ...

show abstract