Alcohol Intake Thresholds Among Individuals With Steatotic Liver Disease

Yeo, Yee Hui; Zhu, Yixuan; Arab, Juan Pablo; Ni, Wenjing; Xu, Xiaoming; Shi, Junping; Li, Jie

doi:10.1001/jamanetworkopen.2023.47548

JAMA Netw Open

2023

DOI: 10.1001/jamanetworkopen.2023.47548

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Alcohol Intake Thresholds Among Individuals With Steatotic Liver Disease

Yee Hui Yeo,

Yixuan Zhu,

Juan Pablo Arab

et al.

Abstract: This cohort study aims to elucidate the dose-dependent association of alcohol use with progression of steatotic liver disease using a noninvasive, low-cost method.

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2024

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Cited by 3 publications

References 6 publications

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The steatotic liver disease burden paradox: unravelling the key role of alcohol

Torp,

Israelsen,

Krag

2024

Nat Rev Gastroenterol Hepatol

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The steatotic liver disease burden paradox: unravelling the key role of alcohol

Torp,

Israelsen,

Krag

2024

Nat Rev Gastroenterol Hepatol

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Alcohol-Associated Liver Disease: Managing the Dual Pathology of Liver Disease and of Alcohol Use Disorder

Arab,

Louvet,

Thiele

et al. 2024

Gastroenterology

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Combined impact of alcohol consumption and metabolic syndrome on liver dysfunction in an elderly Chinese population

Zhao,

Yuan,

Lin

et al. 2024

Diabetol Metab Syndr

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Alcohol consumption and metabolic syndrome(MetS), both prevalent in the general population, frequently co-occur. They are recognized as significant contributors to liver dysfunction, yet their combined effect is often challenging to delineate. This study delves into the compounding influence of alcohol consumption and metabolic disorder on liver dysfunction within an elderly demographic in Zhejiang Province, China. Our findings spotlight a heightened risk of liver dysfunction among females, younger individuals, rural dwellers, those with minimal educational attainment, single individuals, and those diagnosed with MetS. We also discerned a positive correlation correlation between the number of MetS components and the propensity for liver dysfunction. Furthermore, the risk of liver dysfunction escalated in tandem with the frequency of alcohol consumption. Interestingly, a prolonged abstinence period (≥ 5 years) seemed to mitigate this risk. Our research underscores the significance of refraining from excessive alcohol consumption, embracing a healthy lifestyle, and managing MetS components-especially triglyceride levels-for effective prevention of liver dysfunction.

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Alcohol Intake Thresholds Among Individuals With Steatotic Liver Disease

Abstract: This cohort study aims to elucidate the dose-dependent association of alcohol use with progression of steatotic liver disease using a noninvasive, low-cost method.

Cited by 3 publications

References 6 publications

The steatotic liver disease burden paradox: unravelling the key role of alcohol

The steatotic liver disease burden paradox: unravelling the key role of alcohol

Alcohol-Associated Liver Disease: Managing the Dual Pathology of Liver Disease and of Alcohol Use Disorder

Combined impact of alcohol consumption and metabolic syndrome on liver dysfunction in an elderly Chinese population

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